HIV i-Base

Drug interactions

Drug interactions between antiretroviral drugs and other medications are complicated. This is a specialist area, often with limited research.

The following sites include drug-interaction resources.

Key UK publication listing the selection and use of medicines in the UK.

A leading expert resource that includes an online interaction database and summary print charts. This group produces a summary report from each major HIV conference and a monthly reviews of related medical journals.

Database of drug antiretroviral interactions from the University of California, San Francisco HIV inSite online resource.

Specialist HIV commercial laboratory in the UK providing therapeutic drug monitoring (TDM) testing for antiretrovirals and other HIV-related drugs. Also offers genetic, pharmacogentic, virology and immunology tests.

Overview guideline covering main HIV interaction issues that includes a summary table of inducers, inhibitors and substrates of four main P450 enzymes: 1A2, 2C19, 2D6 and 3A4 and another table on the route of elimination for each ARV.

Also includes tables on ARVs and recreational drugs, ARVs and psychotropic medicines,