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Guides Introduction to combination therapy

How do the drugs work?

HIV drugs work by stopping the virus from making copies of itself. This brings viral load down to tiny levels.

Your immune system (including your CD4 cells) then has a chance to become stronger again.

When not on treatment, your immune system is working in overdrive. HIV infects CD4 cells to make more virus. Your body produces new CD4 cells to fight the virus but HIV just uses these cells to keep reproducing. It is like a dog chasing it’s own tail!

This cycle of immune activation is also thought to lead to other health complications. It is one of the reasons that people are now using treatment earlier. Effective treatment stops this over activation.

There are now over 26 drugs that work in at least six stages of the HIV life cycle.

When not on treatment, your immune system works in overdrive

Tail wags dog


April 2012

Decisions relating to your treatment should always be taken in consultation with your doctor. Information in this guide is intended to support those discussions.

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