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• Impact of antiretroviral therapy on incidence of pregnancy among HIV-infected women in Sub-Saharan Africa: a cohort study - Myer L et al.

A multicountry cohort study in sub-Saharan Africa by Landon Myer and colleagues reveals higher pregnancy rates in HIV-infected women on antiretroviral therapy (ART).

• Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating Antiretroviral Therapy—The CASCADE Collaboration: A Collaboration of 23 Cohort Studies - Wolbers M et al.

Analysing data from several thousand cohort study participants, Marcel Wolbers and colleagues find that the rate of CD4 T cell decline is not useful in deciding when to start HIV treatment.

• Effectiveness of Non-nucleoside Reverse-Transcriptase Inhibitor-Based Antiretroviral Therapy in Women Previously Exposed to a Single Intrapartum Dose of Nevirapine: A Multi-country, Prospective Cohort Study - Stringer JAS et al.

In a comparative cohort study, Jeffrey Stringer and colleagues investigate the risk of ART failure in women who received single-dose nevirapine for PMTCT, and assess the duration of increased risk.

• Causes of Acute Hospitalization in Adolescence: Burden and Spectrum of HIV-Related Morbidity in a Country with an Early-Onset and Severe HIV Epidemic: A Prospective Survey - Ferrand RA et al.

Rashida Ferrand and colleagues show that HIV infection is the commonest cause of hospitalisation among adolescents in a high HIV prevalence setting.