The 4th edition of the WHO guidelines includes 6 months of rifampicin in the initial phase of treatment as opposed to just 2 months. Wherever feasible, daily dosing is recommended throughout the course of therapy.

Other recommendations include provider initiated TB testing, and drug susceptibility testing (DST) for all previously treated TB patients at or before the start of treatment.

All HIV-positive patients with active TB should receive antiretrovirals.

World Health Organisation. Treatment of tuberculosis guidelines. Forth edition:

http://www.who.int/tb/publications/tb_treatmentguidelines/en/index.html