15 June 2005

Contents

Conference reports

11th BHIVA and BASSH joint annual conference, 22-25 April 2005, Dublin

Long-awaited UK pregnancy guidelines now updated; pregnancy studies in Dublin

Underdosing of ARVs in children: results from CHIPS cohort

Sexual transmission and response to treatment in acute HCV infection in HIV-positive gay men coinfected with HIV

Levels of efavirenz 10-fold above minimum target level despite coadministration with rifampicin

Schistosomiasis after immune reconstitution: symptoms appear as HAART side effects

6th International Workshop on Clinical Pharmacology of HIV Therapy, 28-30 April 2005, Quebec, Canada

Effect of age/menopause on lopinavir and efavirenz concentrations in women

Effect of age on lopinavir concentrations

Gender and pharmacokinetics of saquinavir

Dosing nevirapine in children

Intracellular NRTI-triphosphate levels in children are similar to adults

Efavirenz and rifampicin: lower body weight associated with higher concentrations

Summary of drug-drug interaction studies

Responses to atazanavir, Kaletra and side effects

Antiretrovirals

500mg saquinavir (Invirase) approved in Europe

Roche to withdraw saquinavir soft gel caps (Fortovase)

FDA approve lopinavir/r once daily for treatment naive patients

Safety data for tenofovir updated

FDA approve entecavir for HBV

Efavirenz warning in pregnancy strengthened

New ritonavir interactions

FDA advisory committee recommends approval for tipranavir – material from hearing online

Application for meltrex formulation of Kaletra submitted to the FDA

Treatment access

MSF criticises Brazilian government for failing to break antiretroviral patents

Russian activists imprisoned for asking for treatment – letters of support requested

Guidelines

US adult treatment guidelines updated (2005)

On the web

TAC electronic newsletter

Articles from AIDS Treatment News

AIDS Vaccine Advocacy Coalition (AVAC) publishes new AIDS Vaccine Handbook

WHO lists reliable web sites on vaccines