HTB

Side effects

Vancouver researchers urge caution with combinations of lipid drugs

Three-year renal safety with tenofovir; cystatin may be a useful marker

Efficacy of acetyl-L-carnitine for antiretroviral toxic neuropathy

Oral uridine to treat mitochondrial toxicity

Phase II results show ThGRF could be safe, effective treatment for lipodystrophy, says company

Reversibility of lipoatrophy in HIV patients 2 years after switching from a thymidine analogue to abacavir

Diabetes and HIV and HCV; aging/HIV and diabetes

Eating grapefruit triggers statin-related rhabdomyolysis

FDA panel recommends approval of New-fill

Lipodystrophy regresses in three patients switched to atazanavir

Race affects absorption and clearance of efavirenz

Update on peripheral neuropathy in HIV-infection

Smoking marijuana provides analgesic effect on HIV neuropathy

Two D:A:D updates: cardiovascular risk from HAART, and predictors of hypertension and changes in blood pressure

Low-dose rHGH maintains reductions in abdominal fat for 60 weeks

Rosiglitazone shows no benefit for lipoatrophy

Importance of dietary management in treating lipid disorders: soy diets may offer comparable effect as statins

Lower doses of d4T produce similar efficacy and reduced side effects

Switching from efavirenz to nevirapine to avoid CNS side effects

Intrauterine exposure to efavirenz

Increased risk of myocardial infarction associated with duration of protease inhibitor treatment

Newer nucleoside analogues show fewer adverse effects

Testosterone therapy prevents loss of lean body mass, improves mood and libido in HIV positive women and increases bone mineral density in HIV positive men

Only time with HIV infection and not specific antiretroviral therapy is associated with decreased bone mineral density

Rosiglitazone with insulin resistance

Uridine treatment for mitochondrial toxicity

Severe efavirenz psychotic events

Uridine as a potential treatment for NRTI related mitochondrial toxicity

Long term exposure to nucleoside analogues and peripheral nerve function

Step-wise intervention eases diarrhoea linked to PI nelfinavir (Viracept) therapy

Bone mineral metabolism and HIV-infection

FDA says some follow-up drug studies are never started

Lamotrigine shows some benefit for HIV-associated painful sensory neuropathies

Women: sexual function and relationships

High levels of gout may be linked to HAART

Tenofovir side effects

HIV-positive patients sustain acute myocardial infarction at a young age and have a benign in-hospital course

Cardiovascular and cerebrovascular events in patients treated for HIV infection

Severe hepatotoxicity during ART: incidence, liver histology, and outcome

Peripheral neuropathy in HIV disease: Lactate levels may help determine if nucleoside toxicity is a contributing factor

Less diarrhoea and bioequivalence with the new nelfinavir 625mg tablet

The potential for probenecid to have a serious interaction with HIV-1 protease inhibitors

Tenofovir and renal tubular dysfunction

Approaches to treatment of lipodystrophy

Surgery for buffalo hump shows variable results depending on method

Other studies – nucleosides and switching to abacavir; importance of lipoatrophy and buffalo hump

HAART to HEART: cardiovascular risk in HIV

Alendronate, vitamin D and calcium are safe and effective treatment for HIV-associated bone loss

Bone loss and fat loss are closely related in HIV patients on HAART

Pegylated interferon associated with eye disorders

Efavirenz effects worse than reported, study says

Protease inhibitors and cardiovascular outcomes in patients with HIV-1

HIV protease inhibitors promote atherosclerosis independent of dyslipidemia

Comparison of the efficacy and safety of tenofovir vs. d4T when used in combination with 3TC and efavirenz in ARV-naive patients

Safety profile of tenofovir in treatment-experienced patients

Perspectives on hormonal, mitochondrial and metabolic changes

IAS panel issues first guidelines for HIV and HIV drug-related metabolic complications (2002)

Side effects are a common cause of intentional non adherence to HAART

Adverse drug reactions and lipodystrophy in children

Lipodystrophy and adverse drug reaction data presented at the 42nd ICAAC

A range of treatments for facial lipoatrophy

Tamoxifen for male breast enlargement?

Diet can help reduce lipid levels in people with HAART-related dyslipemia

Lipodystrophy syndrome and self-assessment of wellbeing and physical appearance in HIV-positive patients

Abacavir hypersensitivity reactions in patients who rechallenge after interruptions for reasons other than hypersensitivity

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