Non-standard combinations: dolutegravir/rilpivirine (Juluca)

Alternatives to two nukes plus a third drug are sometimes used in individual cases or in research.

If you are already using an unusual combination that is working well, you do not need to change treatment unless there are reasons to do so.

Several studies are looking at two-drug combinations.

Please ask your doctor or contact i-Base if you are unsure about your current drugs.


Juluca is the brand name for a two-drug combination of dolutegravir plus rilpivirine in a single tablet.  

Juluca was approved as a switch option for people who have undetectable viral load for more than six months on their first ART.

Last updated: 1 October 2019.