{"id":13352,"date":"2025-11-01T12:00:24","date_gmt":"2025-11-01T12:00:24","guid":{"rendered":"http:\/\/i-base.info\/guides\/?page_id=13352"},"modified":"2025-11-20T13:22:43","modified_gmt":"2025-11-20T13:22:43","slug":"prep-for-trans-and-non-binary-people","status":"publish","type":"page","link":"https:\/\/i-base.info\/guides\/prep\/prep-for-trans-and-non-binary-people","title":{"rendered":"PrEP for trans and non-binary people"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-16301\" src=\"https:\/\/i-base.info\/guides\/wp-content\/uploads\/2022\/08\/logos-for-prep.png\" alt=\"\" width=\"200\" height=\"238\" \/><\/p>\n<p><b>PrEP is just as safe and effective whether you are transgender, non-binary or cisgender.<\/b><\/p>\n<p>This is the case for both oral and injectable PrEP.<\/p>\n<p>Dosing choices for oral depend on the type of sex, although daily dosing has generally been recommended.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p>Everyone can start PrEP with a double dose (two pills). This works in two hours rather than the old advice to take daily PrEP for 7 days before sex.<\/p>\n<p>After sex, take daily PrEP (one pill) for seven days if you want to use event-based dosing (called 2:7). If you want to continue on daily PrEP, you just need to take at least 4 daily doses each week.<\/p>\n<p>Anyone having insertive or receptive anal sex or insertive vaginal\/frontal sex can use 2:1:1 event-based dosing. Event-based dosing using 2:7 dosing is recommended for receptive vaginal\/frontal sex.<\/p>\n<p><em>Note: Some researchers think that 2:7 dosing is more pills than are needed and\u00a0that fewer doses after sex would also be okay, for example, 2:1:1:1 dosing. This is based on drug levels reached by this dosing though and isn&#8217;t included in guidelines.<\/em><\/p>\n<p>Please see these links.<\/p>\n<ul>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/how-to-take-prep\">How to start and stop PrEP<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/daily-prep-for-anal-and-vaginal-sex\">Daily PrEP dosing<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/on-demand\">Event-based dosing<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/real-life-examples-for-on-demand-dosing\">Examples of event-based 2:1:1 and 2:7 dosing<\/a><\/li>\n<\/ul>\n<h2>PrEP is very safe with hormone treatment<\/h2>\n<p>Even though you might worry about drug interactions, neither your hormone or PrEP levels will be affected.<\/p>\n<p>Liverpool University produces an excellent guide to drug interactions between hormone treatments and other HIV meds:<\/p>\n<p><a href=\"http:\/\/www.hiv-druginteractions.org\/printable_charts\">hiv-druginteractions.org\/printable_charts<\/a><\/p>\n<p>Ongoing studies are looking at other aspects of PrEP in trans women and men.<\/p>\n<h2>Useful links<\/h2>\n<p><strong>CliniQ<\/strong><\/p>\n<p><a href=\"http:\/\/www.cliniq.org.uk\">CliniQ<\/a> is a London-based specialist clinic providing sexual health and well-being services for trans people.<\/p>\n<p><strong>56T clinic<\/strong><\/p>\n<p><a href=\"https:\/\/www.dean.st\/trans-non-binary\/\">56T clinic<\/a> at Dean Street has a very busy PrEP service for trans and non-binary people.<\/p>\n<p><strong>Clinic T<\/strong><\/p>\n<p><a href=\"https:\/\/brightonsexualhealth.com\/service\/clinic-t\">Clinic T<\/a> is a trans and non-binary friendly sexual health service in Brighton.<\/p>\n<p><strong>Indigo Gender Service<\/strong><\/p>\n<p><a href=\"https:\/\/indigogenderservice.uk\/\">Indigo Gender Service<\/a> is an NHS trans healthcare service in Manchester.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PrEP is just as safe and effective whether you are transgender, non-binary or cisgender. This is the case for both oral and injectable PrEP. Dosing choices for oral depend on the type of sex, although daily dosing has generally been &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":11507,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"page-guides.php","meta":{"footnotes":""},"class_list":["post-13352","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/13352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/comments?post=13352"}],"version-history":[{"count":8,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/13352\/revisions"}],"predecessor-version":[{"id":19130,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/13352\/revisions\/19130"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/11507"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/media?parent=13352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}