{"id":2334,"date":"2025-01-01T12:00:01","date_gmt":"2025-01-01T12:00:01","guid":{"rendered":"http:\/\/moomango.co.uk\/guides\/?page_id=2334"},"modified":"2025-01-15T12:25:32","modified_gmt":"2025-01-15T12:25:32","slug":"general-principles","status":"publish","type":"page","link":"https:\/\/i-base.info\/guides\/changing\/general-principles","title":{"rendered":"General principles"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-15453\" src=\"https:\/\/i-base.info\/guides\/wp-content\/uploads\/2025\/01\/ChangingJan2025COVER.png\" alt=\"\" width=\"144\" height=\"201\" \/>Four general ideas increase the chance of your next treatment working.<\/strong><\/p>\n<ol>\n<li>Using drugs from a new class.<\/li>\n<li>Using drugs from classes you have used before but did not develop resistance to.<\/li>\n<li>Perhaps using more, rather than fewer drugs.<\/li>\n<li>Perhaps using a higher dose of some drugs.<\/li>\n<\/ol>\n<p>Treatment guidelines also outline ways to choose new drugs. See: <a href=\"http:\/\/www.bhiva.org\">www.bhiva.org<\/a>.<\/p>\n<p>Your new ART will also depend on the <b><a href=\"https:\/\/i-base.info\/guides\/changing\/reasons\">reason that your previous combination failed<\/a>\u00a0and on the <\/b><b><a href=\"https:\/\/i-base.info\/guides\/changing\/other-tests\">results of other tests<\/a><\/b>.<\/p>\n<p>Resistance tests will help pick meds that may work, even when you have some resistance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Four general ideas increase the chance of your next treatment working. Using drugs from a new class. Using drugs from classes you have used before but did not develop resistance to. Perhaps using more, rather than fewer drugs. Perhaps using &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":10,"menu_order":27,"comment_status":"closed","ping_status":"closed","template":"page-guides.php","meta":{"footnotes":""},"class_list":["post-2334","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/2334","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/comments?post=2334"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/2334\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/10"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/media?parent=2334"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}