{"id":2375,"date":"2025-01-01T12:00:56","date_gmt":"2025-01-01T12:00:56","guid":{"rendered":"http:\/\/moomango.co.uk\/guides\/?page_id=2375"},"modified":"2025-01-20T14:50:41","modified_gmt":"2025-01-20T14:50:41","slug":"intensify-treatment","status":"publish","type":"page","link":"https:\/\/i-base.info\/guides\/changing\/intensify-treatment","title":{"rendered":"Intensify treatment"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-15453\" src=\"https:\/\/i-base.info\/guides\/wp-content\/uploads\/2025\/01\/ChangingJan2025COVER.png\" alt=\"\" width=\"144\" height=\"201\" \/>In rare circumstances, you may be able to add a single new drug to your existing ART.\u00a0<\/strong><\/p>\n<p>This can include:<\/p>\n<ul>\n<li>Adding a drug you have never used.<\/li>\n<li>Adding a drug you have already used but which may still work, perhaps becasue you did not develop resistance.<\/li>\n<\/ul>\n<p>You should only aim to intensify by adding a completely new drug <strong>while your viral load is still falling or if it has stabilised<\/strong><em>.<\/em><\/p>\n<p>If you intensify after your viral load has started to rebound or when it is higher than 500 copies\/mL, you may be adding monotherapy to a failing combination. This risks developing resistance to the new drug.<\/p>\n<p>You can also intensify by <strong>boosting<\/strong> current drugs, for example:<\/p>\n<ul>\n<li>Add a drug that boosts the levels of one of your current drugs.<\/li>\n<\/ul>\n<ul>\n<li>Increase the dose of a drug. This is usually only if drug level monitoring (see <a href=\"https:\/\/i-base.info\/guides\/changing\/tdm\">TDM (Therapeutic Drug Monitoring)<\/a>\u00a0has\u00a0shown that you do not have high enough drug levels using the regular dose.<\/li>\n<\/ul>\n<p>If it is done early, intensification may reduce viral load below detection again.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In rare circumstances, you may be able to add a single new drug to your existing ART.\u00a0 This can include: Adding a drug you have never used. Adding a drug you have already used but which may still work, perhaps &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":10,"menu_order":34,"comment_status":"closed","ping_status":"closed","template":"page-guides.php","meta":{"footnotes":""},"class_list":["post-2375","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/2375","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/comments?post=2375"}],"version-history":[{"count":1,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/2375\/revisions"}],"predecessor-version":[{"id":18434,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/2375\/revisions\/18434"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/10"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/media?parent=2375"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}