{"id":244,"date":"2024-11-01T12:00:01","date_gmt":"2024-11-01T12:00:01","guid":{"rendered":"http:\/\/localhost\/new\/guides\/?page_id=244"},"modified":"2024-11-22T23:12:28","modified_gmt":"2024-11-22T23:12:28","slug":"types-of-hiv-drugs","status":"publish","type":"page","link":"https:\/\/i-base.info\/guides\/starting\/types-of-hiv-drugs","title":{"rendered":"Main types of HIV drugs"},"content":{"rendered":"<p><strong>There are many types (or classes) of ARVs \u2013 and others are in development. Each class works at a different stage of the HIV life cycle.<\/strong><\/p>\n<p>Every combination uses at least two different types of drugs.<\/p>\n<p>This website has<strong> <a href=\"https:\/\/i-base.info\/guides\/category\/arvs\">info on each HIV drug<\/a> <\/strong>\u2013 old or new.<\/p>\n<table border=\"0\" summary=\"Seven classes of HIV drugs: RTIs or nukes, non-nukes (NNRTIs), PIs, fusion inhibitors, CCR5 inhibitors and integrase inhibitors (INIs) and two pharmokinetic boosters\">\n<caption>Table 1: Main types of HIV drugs<\/caption>\n<tbody>\n<tr>\n<th scope=\"col\">Abbreviation<\/th>\n<th scope=\"col\">Full name(s)<\/th>\n<\/tr>\n<tr>\n<td><strong>NRTIs\/NtRTIs (&#8216;nukes&#8217;)<\/strong><\/td>\n<td>nucleoside\/tide reverse transcriptase inhibitors or nucleoside\/tide analogues<\/td>\n<\/tr>\n<tr>\n<td><strong>NNRTIs<br \/>\n<\/strong><strong>(&#8216;non-nukes&#8217;)<\/strong><\/td>\n<td>non-nucleoside reverse transcriptase inhibitors<\/td>\n<\/tr>\n<tr>\n<td><strong>PIs<\/strong><\/td>\n<td>protease inhibitors<\/td>\n<\/tr>\n<tr>\n<td><strong>INIs (or INSTIs)<\/strong><\/td>\n<td>integrase strand transfer inhibitors<\/td>\n<\/tr>\n<tr>\n<td><strong>CCR5 inhibitors<\/strong><\/td>\n<td>CCR5 inhibitors are a type of entry inhibitor<\/td>\n<\/tr>\n<tr>\n<td><strong>mAbs<\/strong><\/td>\n<td>monoclonal antibodies \u2013 which also block entry to the CD4 cell<\/td>\n<\/tr>\n<tr>\n<td><strong>Fusion inhibitors<\/strong><\/td>\n<td>fusion inhibitors are a type of entry inhibitor<\/td>\n<\/tr>\n<tr>\n<td><strong>PK boosters<\/strong><\/td>\n<td>Ritonavir or cobicistat are included in some combinations to boost another drug<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>There are more than 30 HIV drugs and formulations. Luckily, only a few combinations are commonly used.<\/p>\n<p>See also: <strong><a href=\".\/starting\/hiv-life-cycle\">Figure 5: HIV life cycle &#8211; how drugs work in different ways<\/a>.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>There are many types (or classes) of ARVs \u2013 and others are in development. Each class works at a different stage of the HIV life cycle. Every combination uses at least two different types of drugs. This website has info &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":1547,"menu_order":44,"comment_status":"open","ping_status":"closed","template":"page-guides.php","meta":{"footnotes":""},"class_list":["post-244","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/comments?post=244"}],"version-history":[{"count":4,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/244\/revisions"}],"predecessor-version":[{"id":17737,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/244\/revisions\/17737"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/1547"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/media?parent=244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}