{"id":4910,"date":"2025-01-01T12:00:03","date_gmt":"2025-01-01T12:00:03","guid":{"rendered":"http:\/\/i-base.info\/guides\/?page_id=4910"},"modified":"2025-01-15T12:22:20","modified_gmt":"2025-01-15T12:22:20","slug":"viral-tropism","status":"publish","type":"page","link":"https:\/\/i-base.info\/guides\/changing\/viral-tropism","title":{"rendered":"Viral tropism"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-15453\" src=\"https:\/\/i-base.info\/guides\/wp-content\/uploads\/2025\/01\/ChangingJan2025COVER.png\" alt=\"\" width=\"144\" height=\"201\" \/>This test is only used if you are going to use a drug called maraviroc. <\/strong><\/p>\n<p><strong>Maraviroc is a CCR5 inhibitor that works at the early stage of the HIV lifecycle.<\/strong><\/p>\n<p>In the UK and Europe, tropism is tested using a genotype resistance test. A special type of resistance test (testing proviral DNA) can be used if your viral load is low or undetectable.<\/p>\n<p><b><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21429803\">European guidelines for HIV tropism testing<\/a><\/b>. (2011)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This test is only used if you are going to use a drug called maraviroc. Maraviroc is a CCR5 inhibitor that works at the early stage of the HIV lifecycle. In the UK and Europe, tropism is tested using a &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":10,"menu_order":22,"comment_status":"closed","ping_status":"closed","template":"page-guides.php","meta":{"footnotes":""},"class_list":["post-4910","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/4910","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/comments?post=4910"}],"version-history":[{"count":4,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/4910\/revisions"}],"predecessor-version":[{"id":18402,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/4910\/revisions\/18402"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/pages\/10"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/guides\/wp-json\/wp\/v2\/media?parent=4910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}