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HTB
2000
June
15
HTB
15 June 2000
Contents
Treatment alerts
Safety warning on amprenavir oral liquid
Conference reports
Exercise testing in HIV patients with random increased lactic acid levels: evidence for a reduced anaerobic threshold with a pattern of mitochondrial dysfunction
Antiretrovirals
Didanosine systemic exposure in children similar with or without food, high interpatient variability suggests TDM to titrate individual dosages
Low level HIV replication despite good virological response may explain CD4+ cell decline in a patient receiving combination nucleoside analogue therapy
Treatment strategies
Phase III study of GM-CSF in advanced HIV disease
Women's health
Women and HIV: is it really a biological difference?
Paediatric care
Antiretroviral therapy improves thymic output in some HIV-infected children
Guidelines
HIV drug resistance testing: update
Side effects
Mitochondrial toxicities of nucleoside reverse transcriptase inhibitors
Accelerated bone mineral loss in HIV-positive patients receiving potent antiretroviral therapy
Irreversible renal dysfunction linked to long-term indinavir therapy
OIs, coinfections and complications
HIV-related anal cancer incidence increased in long-term survivors
Basic science and immunology
CD8+-cell antiviral factors not restricted to cytotoxic T cells induced during HIV
Other news
Obiturary: Kiyoshi Kuromiya, 1943-2000
What is Armenicum?
Drug companies fail to conduct necessary post-marketing studies
Correspondence
Letter: Project Inform nelfinavir potency concerns article