{"id":11115,"date":"2003-05-01T16:04:41","date_gmt":"2003-05-01T16:04:41","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=11115"},"modified":"2014-05-28T12:54:49","modified_gmt":"2014-05-28T12:54:49","slug":"4th-international-workshop-on-clinical-pharmacology-of-hiv-therapy","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/11115","title":{"rendered":"4th International Workshop on Clinical Pharmacology of HIV Therapy, 27-29 March 2003, Cannes, France"},"content":{"rendered":"<p><strong>Stephen Taylor, for HIV i-Base<\/strong><\/p>\n<p><strong>The fourth in this annual series of workshops returned to Europe, after having made its first appearance in the USA last year.<\/strong><\/p>\n<p>This spring meeting marks one of the year\u2019s highlights for those interested in HIV Pharmacology and is usually a perfect forum to generate active research discussions. This year approximately 150 delegates composed of HIV clinicians, pharmacists, researchers, activists and industry travelled to the French Riviera, to share the latest data concerning HIV pharmacology.<\/p>\n<p>Following the presentation of the 2NN study at the Retrovirus conference earlier this year participants were particularly eager to hear of any drug concentration response or toxicity relationships pertaining to the NNRTIs and whether therapeutic drug monitoring (TDM) of these agents will be of potential benefit. Several papers attempted to shed some light on the pharmacokinetic\/pharmacodynamic (PK\/PD) relationships of the NNRTIs.<\/p>\n<p>These reports cannot hope to cover the wealth of papers presented at this workshop (the abstracts will shortly be posted on HIV-Pharmacology.com) but instead cover some of the papers with most potential clinical relevance presented at the meeting. These include:<\/p>\n<ul>\n<li><a title=\"Permanent link to Can low NVP plasma concentrations explain the results seen in the EFV and NVP containing arms of the NARVAL study?\" href=\"https:\/\/i-base.info\/htb\/11110\" rel=\"bookmark\">Can low NVP plasma concentrations explain the results seen in the EFV and NVP containing arms of the NARVAL study?<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Up to one third of patients receiving standard doses of NNRTIs may be being underdosed\" href=\"https:\/\/i-base.info\/htb\/11113\" rel=\"bookmark\">Up to one third of patients receiving standard doses of NNRTIs may be being underdosed<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Nelfinavir concentrations are significantly higher in HIV\/HCV co-infected patients with cirrhosis\" href=\"https:\/\/i-base.info\/htb\/11108\" rel=\"bookmark\">Nelfinavir concentrations are significantly higher in HIV\/HCV co-infected patients with cirrhosis<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Less diarrhoea and bioequivalence with the new nelfinavir 625mg tablet\" href=\"https:\/\/i-base.info\/htb\/11106\" rel=\"bookmark\">Less diarrhoea and bioequivalence with the new nelfinavir 625mg tablet<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to The potential for probenecid to have a serious interaction with HIV-1 protease inhibitors\" href=\"https:\/\/i-base.info\/htb\/11104\" rel=\"bookmark\">The potential for probenecid to have a serious interaction with HIV-1 protease inhibitors<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to PK studies reveal significant sex\/gender differences\" href=\"https:\/\/i-base.info\/htb\/11100\" rel=\"bookmark\">PK studies reveal significant sex\/gender differences<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Pregnancy-related PK studies\" href=\"https:\/\/i-base.info\/htb\/11098\" rel=\"bookmark\">Pregnancy-related PK studies<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to New test to measure intracellular levels of nucleosides\" href=\"https:\/\/i-base.info\/htb\/11096\" rel=\"bookmark\">New test to measure intracellular levels of nucleosides<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Case studies for therapeutic drug monitoring (TDM)\" href=\"https:\/\/i-base.info\/htb\/11094\" rel=\"bookmark\">Case studies for therapeutic drug monitoring (TDM)<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Launch of guide to the use of drug level monitoring\" href=\"https:\/\/i-base.info\/htb\/11091\" rel=\"bookmark\">Launch of guide to the use of drug level monitoring<\/a><\/li>\n<\/ul>\n<p>This year\u2019s workshop provided clinicians and pharmacists with much to digest and much new data that has potentially important clinical implications. The meeting continues to provide an important forum in which to present both basic science research as well as pharmacologically driven studies. It is likely only to grow in importance within the HIV calendar.<\/p>\n<p>Full content of the meeting including poster and abstracts, together with a conference report will be available at:<br \/>\n<a href=\"http:\/\/www.HIVpharmacology.com\"> http:\/\/www.HIVpharmacology.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Stephen Taylor, for HIV i-Base The fourth in this annual series of workshops returned to Europe, after having made its first appearance in the USA last year. This spring meeting marks one of the year\u2019s highlights for those interested in &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,34],"tags":[12,140],"class_list":["post-11115","post","type-post","status-publish","format-standard","hentry","category-conference-reports","category-pk-and-drug-interactions","tag-conference-index","tag-pk-workshop-2003"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/11115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=11115"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/11115\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=11115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=11115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=11115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}