{"id":13758,"date":"2010-08-26T06:22:43","date_gmt":"2010-08-26T06:22:43","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=13758"},"modified":"2012-07-27T11:41:32","modified_gmt":"2012-07-27T11:41:32","slug":"atazanavirr-approved-in-europe-for-children-aged-6-to-18-years","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/13758","title":{"rendered":"Atazanavir\/r approved in Europefor children aged 6 to 18 years"},"content":{"rendered":"<p>On 7 July 2010, the use of boosted atazanavir was extended in Europe to include children aged 6\u009618 years old, weighing &gt;15kg. [1]<\/p>\n<p>This was based on results from the open label multicentre PACTG 1020A study. [2]<\/p>\n<p>The study included 182 naive and experienced paediatric patients aged 6 to 18 years old, using once daily atazanavir, with (n=141) or without (n=41) ritonavir, in combination with two NRTIs. The data from the 41 patients using ritonavir-boosting (n=16 naive and 25) supported this new paediatric indication.<\/p>\n<p>The recommended atazanavir\/ritonavir doses by body weight are 150 mg\/100 mg (15kg\u0096less than 20 kg) and 200 mg\/100 mg (20 kg\u0096less than 40 kg); with children  weighing over 40 kg recommended to use the standard adult dose of 300 mg\/100 mg.<\/p>\n<p>Source: BMS press release (07 July 2010).<a href=\"http:\/\/www.pharmiweb.com\/pressreleases\/pressrel.asp?ROW_ID=24756\">http:\/\/www.pharmiweb.com\/pressreleases\/pressrel.asp?ROW_ID=24756<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>On 7 July 2010, the use of boosted atazanavir was extended in Europe to include children aged 6\u009618 years old, weighing &gt;15kg. [1] This was based on results from the open label multicentre PACTG 1020A study. [2] The study included &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,38,32],"tags":[],"class_list":["post-13758","post","type-post","status-publish","format-standard","hentry","category-antiretrovirals","category-treatment-access","category-paediatric-care"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/13758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=13758"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/13758\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=13758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=13758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=13758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}