{"id":13780,"date":"2010-08-26T07:23:32","date_gmt":"2010-08-26T07:23:32","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=13780"},"modified":"2012-07-27T11:48:09","modified_gmt":"2012-07-27T11:48:09","slug":"smoking-and-atazanavir-levels","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/13780","title":{"rendered":"Smoking and atazanavir levels"},"content":{"rendered":"<p><a href=\"http:\/\/www.hiv-druginteractions.org\"><strong>www.hiv-druginteractions.org<\/strong><\/a><\/p>\n<p>The effect of tobacco smoking on atazanavir trough concentrations was assessed in a cohort of 416 patients, of which 246 were smokers and 170 were non-smokers or ex smokers. No association was found between smoking history and atazanavir trough concentration: median (IQR) trough concentrations were 571 (329-960) ng\/mL for smokers and 536.5 (323-1030) ng\/mLfor non\/ex-smokers (p=0.85).<\/p>\n<p>In multivariate analysis there were no significant variables associated to atazanavir trough concentration and smoking history.<\/p>\n<p>Source: IAS report (20 July 2010) <a href=\"http:\/\/www.hiv-druginteractions.org\">www.hiv-druginteractions.org<\/a><\/p>\n<p>Ref: Guillemi S et al. Does smoking tobacco affect atazanavir exposure in HIV-infected individuals? 18th IAS Conference, 18\u009623 July 2010, Vienna. Poster abstract WEPE0095.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>www.hiv-druginteractions.org The effect of tobacco smoking on atazanavir trough concentrations was assessed in a cohort of 416 patients, of which 246 were smokers and 170 were non-smokers or ex smokers. No association was found between smoking history and atazanavir trough &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,34],"tags":[153],"class_list":["post-13780","post","type-post","status-publish","format-standard","hentry","category-conference-reports","category-pk-and-drug-interactions","tag-aids-18th-vienna-2010"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/13780","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=13780"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/13780\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=13780"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=13780"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=13780"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}