{"id":14193,"date":"2010-12-01T09:15:18","date_gmt":"2010-12-01T09:15:18","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=14193"},"modified":"2012-07-26T14:39:31","modified_gmt":"2012-07-26T14:39:31","slug":"update-to-us-saquinavir-label","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/14193","title":{"rendered":"Update to US saquinavir label"},"content":{"rendered":"<p>On 23 October the FDA approved label changes for the antiviral drug saquinavir (Invirase), describing a potential change in the electrical activity of the heart when saquinavir is used in combination with ritonavir. Changes in the electrical activity of the heart may lead to abnormal heart rhythms.<\/p>\n<p>The Dear Doctor letter for this change was included in the September\/October issue of HTB.<\/p>\n<p>Links:<\/p>\n<p>Revised saquinavir label<\/p>\n<p><a href=\"http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/020628s033,021785s010lbl.pdf\">http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/020628s033,021785s010lbl.pdf<\/a><\/p>\n<p>Roche issue Dear Doctor letter: Saquinavir prolongation of QT interval. HIV Treatment Bulletin, September\/October 2010.<\/p>\n<p><a href=\"https:\/\/i-base.info\/htb\/13984\">https:\/\/i-base.info\/htb\/13984<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>On 23 October the FDA approved label changes for the antiviral drug saquinavir (Invirase), describing a potential change in the electrical activity of the heart when saquinavir is used in combination with ritonavir. Changes in the electrical activity of the &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,8],"tags":[],"class_list":["post-14193","post","type-post","status-publish","format-standard","hentry","category-antiretrovirals","category-side-effects"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/14193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=14193"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/14193\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=14193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=14193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=14193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}