{"id":16560,"date":"2012-06-01T10:08:25","date_gmt":"2012-06-01T10:08:25","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=16560"},"modified":"2012-07-21T05:41:54","modified_gmt":"2012-07-21T05:41:54","slug":"echinacea-and-etravirine","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/16560","title":{"rendered":"Echinacea and etravirine"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-16567\" title=\"13th PK logo\" src=\"https:\/\/i-base.info\/htb\/files\/2012\/05\/13th-PK-logo.png\" alt=\"\" width=\"160\" height=\"81\" \/>www.drug-interactions.org<\/strong><\/p>\n<p><strong>The botanical echinacea was originally not recommended for HIV positive people because of a negative impact on the immune system. <\/strong><\/p>\n<p>This concern may have been over cautious, though there is little evidence supporting a clinical benefit. A study in 15 HIV positive people reported no effect on etravirine levels (AUC, Cmax and Ctrough increased by 4%, 3% and 3% respectively, when coadministered Echinacea purpurea 500 mg supplement was also taken (500 mg, 3 times daily) for 14 days.<\/p>\n<p>Reference:<\/p>\n<p>Molto J et al. Interaction between echinacea purpurea and etravirine in HIV-infected patients. 13th PK Workshop, Barcelona, 2012. Abstract: P_03.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>www.drug-interactions.org The botanical echinacea was originally not recommended for HIV positive people because of a negative impact on the immune system. This concern may have been over cautious, though there is little evidence supporting a clinical benefit. A study in &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,34],"tags":[136],"class_list":["post-16560","post","type-post","status-publish","format-standard","hentry","category-conference-reports","category-pk-and-drug-interactions","tag-pk-workshop-13th-2012"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/16560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=16560"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/16560\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=16560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=16560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=16560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}