{"id":2074,"date":"2007-12-01T23:49:19","date_gmt":"2007-12-01T22:49:19","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=2074"},"modified":"2019-01-10T15:49:18","modified_gmt":"2019-01-10T15:49:18","slug":"us-updates-guidelines-on-use-of-arvs-during-pregnancy","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/2074","title":{"rendered":"US updates guidelines on use of ARVs during pregnancy (Dec 2007)"},"content":{"rendered":"<p><strong>The Public Health Service Task Force Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV-1 Transmission in the United States have undergone a complete revision and reorganisation to reflect important new information, and to make them more user-friendly.<\/strong><\/p>\n<p>The guidelines have been restructured into principles for medical management of the woman and her infant during the antepartum, intrapartum, and postpartum period, including panel recommendations for each section.<\/p>\n<p>Changes to the report include the following:<\/p>\n<ul>\n<li>Due to contamination with ethyl methane sulfonate (EMS), nelfinavir is no longer recommended for use in pregnant HIV-positive\u00a0women<\/li>\n<li>New sections on antepartum management of HIV-positive\u00a0pregnant women in special situations, including HBV and HCV coinfection<\/li>\n<li>New information on ARV drug choice and continuation during labor, and management of women not receiving antepartum ARVs<\/li>\n<li>New sections on choice and management of infant ARV prophylaxis<\/li>\n<li>Two new tables: \u0093Results of Major Studies on ARV Prophylaxis to Prevent Mother-to-Child HIV Transmission\u0094 and \u0093Clinical Scenario Summary Recommendations for ARV Use by Pregnant HIV-Infected Women and Prevention of Perinatal HIV-1Transmission in the U.S.\u0094<\/li>\n<li>Updated information for emtricitabine, tenofovir, amprenavir, atazanavir, lopinavir\/ritonavir, nelfinavir, maraviroc, and raltegravir in Table 2, \u0093Preclinical &amp; Clinical Data Relevant to the Use of ARVs in Pregnancy\u0094<\/li>\n<li>Updated information for tenofovir, saquinavir-HGC, atazanavir, nelfinavir, maraviroc, and raltegravir in Table 3, \u0093ARV Use in Pregnant HIV-Infected Women: Pharmacokinetic and Toxicity Data in Human Pregnancy and Recommendations for Use in Pregnancy\u0094<\/li>\n<\/ul>\n<p>You can download the guidelines or can request to receive them by e-mail or regular mail on the AIDSinfo website:<\/p>\n<p><a href=\"http:\/\/aidsinfo.nih.gov\">http:\/\/aidsinfo.nih.gov<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Public Health Service Task Force Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV-1 Transmission in the United States have undergone a complete revision and reorganisation to reflect important &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35,23],"tags":[],"class_list":["post-2074","post","type-post","status-publish","format-standard","hentry","category-pmtct-and-maternal-health","category-guidelines"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/2074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=2074"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/2074\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=2074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=2074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=2074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}