{"id":2456,"date":"2007-07-03T22:49:32","date_gmt":"2007-07-03T21:49:32","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=2456"},"modified":"2013-09-20T15:07:26","modified_gmt":"2013-09-20T15:07:26","slug":"the-dynamics-of-hcv-transmission-among-injection-drug-users-in-st-petersburg","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/2456","title":{"rendered":"The dynamics of HCV transmission among injection drug users in St. Petersburg"},"content":{"rendered":"<p><strong>Elijah Paintsil and co-workers from the Sexual Transmission and Acquisition of HIV Cooperative Agreement Program (SATH-CAP) project in St. Petersburg presented findings from a study in which they compared network linkages with linkages among the viral genomes among a group of people with HCV recruited by respondent-driven sampling in St. Petersburg.<\/strong><\/p>\n<p>The investigators reported that sequences from 77 people studied showed 3 main genotypes (3a, 1a, and 1b) circulating in the study population, with a majority of genotype 3a (62%). Genotypes 1b and 1a were 21% and 17%, respectively.<\/p>\n<p>Of the total, 67\/77 samples belonged to 11 recruitment chains of productive seeds or chains with more than 2 people; 4 chains with 6, 4, 2, and 3 people (excluding seeds) had a single genotype (3a); 4 chains with 7, 11, 5, and 4 members (excluding seeds) had multiple genotypes with &gt;50% of them belonging to 3a; 3 chains with 13, 4, and 2 members (excluding seeds) contained discordant genotypes in variable amounts.<\/p>\n<p>They concluded that these data suggest that molecular epidemiological tools could provide data to support or refute transmission within social networks that are exploited in assembling respondent-driven sampling study populations.<\/p>\n<p>They wrote: \u0093The ability of respondent-driven sampling to capture transmission patterns for prevalent infections appears limited, but the two data sets combined could provide a more robust exploration of incident transmissions of infectious diseases like HCV and HIV.\u0094<\/p>\n<p class=\"ref\">Reference:<\/p>\n<p class=\"ref\">Paintsil E, Abdala N, Niccolai L et al. The dynamics of HCV transmission among injection drug users in St. Petersburg, Russia: Sexual Transmission and Acquisition of HIV Cooperative Agreement Program. 14th CROI, 2007, Los Angeles. Abstract 131.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Elijah Paintsil and co-workers from the Sexual Transmission and Acquisition of HIV Cooperative Agreement Program (SATH-CAP) project in St. Petersburg presented findings from a study in which they compared network linkages with linkages among the viral genomes among a group &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[61],"class_list":["post-2456","post","type-post","status-publish","format-standard","hentry","category-conference-reports","tag-croi-2007"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/2456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=2456"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/2456\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=2456"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=2456"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=2456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}