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Polly Clayden, HIV i-Base<\/strong><\/p>\n HIV exposed, uninfected children were more likely to have a lower gestational age and birth weight, and were more likely to be delivered by Caesarean section compared to unexposed controls, according to a Danish nationwide study.<\/strong><\/p>\n Ellen Larsen presented preliminary results on birth related characteristics from a study conducted to evaluate rates, diagnoses, lengths of hospital admission and use of antibiotics among HIV exposed, uninfected children aged 0 to 4 years of age, compared to a matched control group of children not exposed to HIV. These data were shown at the 4th International Workshop on HIV & Women, 2014.<\/p>\n For this analysis the investigators collected information on all births in Denmark from 1 January 2000 to 31 December 2010 from the national registries at Statistics Denmark. They found a total of 712.428 children were born during the time period and 268 children were born to HIV positive mothers.<\/p>\n HIV positive mothers were less likely than HIV negative ones to be married 80% vs 93% and slightly older, mean 32 years, (95% CI 31.4 to 32.7) vs. 31 years, (95% CI 30.7 to30.8). Both comparisons p<0.001. The HIV exposed infants had a shorter mean gestational age, 267 days (95% CI 264 to 269) vs 278 days (95% CI 277 to 278); were more likely to be delivered by Caesarean section, 64% vs. 21%; and had a lower mean birth weight, 3035g (95% CI 2951 to 3121) vs 3478g (95% CI 3477-3480). All comparisons p<0.001.<\/p>\n Smoking habits during pregnancy, completed pregnancies, multiple births, and Apgar score at 10 minutes were similar in both cohorts.<\/p>\n The study will intends to further investigate whether due to these factors there is an increased morbidity in HIV exposed uninfected children. The investigators noted that there might be a need for a closer follow-up of these children.<\/p>\n Reference:<\/p>\n Larsen EM et al. Morbidity among HIV exposed uninfected children compared to children not exposed to HIV – a Danish nationwide study. 4th International Workshop on HIV & Women, Washington DC. 13-14 January 2014. Oral abstract_22.<\/p>\n