{"id":266,"date":"2008-12-26T08:24:11","date_gmt":"2008-12-26T07:24:11","guid":{"rendered":"http:\/\/localhost\/new\/htb\/?p=266"},"modified":"2013-08-23T13:08:00","modified_gmt":"2013-08-23T13:08:00","slug":"us-guidelines-updated-november-2008","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/266","title":{"rendered":"US guidelines updated &#8211; November 2008"},"content":{"rendered":"<p><strong>The US Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents were updated in November.<\/strong><br \/>\n<a href=\"http:\/\/aidsinfo.nih.gov\">http:\/\/aidsinfo.nih.gov<\/a><\/p>\n<ul>\n<li>Changes for treatment naive patients include:\n<ul>\n<li>adding darunavir\/r as a preferred PI;<\/li>\n<li>moving once-daily lopinavir\/r from alternative to preferred PI (except for pregnant women);<\/li>\n<li>moving abacavir+3TC from a preferred to an alternative dual-NRTI because of concerns regarding an increased risk of myocardial infarction in patients with high cardiac risk factors, and virologic potency with baseline viral loads&gt;100,000 copies\/mL;<\/li>\n<li>cautions against unboosted atazanavir+ddI+FTC\/3TC or nevirapine+tenofovir+FTC\/3TC, because of efficacy.<\/li>\n<\/ul>\n<\/li>\n<li>A new section on regimen simplification for virologically suppressed treatment-experienced patients.<\/li>\n<li>The guidelines include an option for 6-monthly CD4 and viral load monitoring once patients who are stable and suppressed on treatment for 2-3 years.<\/li>\n<li>Many tables are updated to include newer drugs and tests.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>The US Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents were updated in November. http:\/\/aidsinfo.nih.gov Changes for treatment naive patients include: adding darunavir\/r as a preferred PI; moving once-daily lopinavir\/r from alternative to preferred PI (except &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[],"class_list":["post-266","post","type-post","status-publish","format-standard","hentry","category-guidelines"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=266"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/266\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=266"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}