{"id":3025,"date":"2006-10-16T08:17:59","date_gmt":"2006-10-16T07:17:59","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=3025"},"modified":"2006-10-16T08:17:59","modified_gmt":"2006-10-16T07:17:59","slug":"8th-international-workshop-on-adverse-drug-effects-and-lipodystrophy-in-hiv-infection-iwadelhi","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/3025","title":{"rendered":"8th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 23-26 September 2006, San Francisco"},"content":{"rendered":"<p><a href=\"https:\/\/i-base.info\/htb\/keyword\/lipodystrophy-workshop-iwadrw-8-san-francisco\">Reports from the workshop<\/a> <\/p>\n<ul>\n<li><a title=\"Permanent link to The role of the metabolic syndrome in HIV\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/919\">The role of the metabolic syndrome in HIV<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Effect of lifestyle modification on risk factors for cardiovascular disease and metabolic syndrome\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/3021\">Effect of lifestyle modification on risk factors for cardiovascular disease and metabolic syndrome<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Pioglitazone reduces peripheral lipoatrophy and improves adipokines without reducing visceral fat\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/3007\">Pioglitazone reduces peripheral lipoatrophy and improves adipokines without reducing visceral fat<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Leptin reduces visceral abdominal tissue (VAT) without reducing limb fat\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/2998\">Leptin reduces visceral abdominal tissue (VAT) without reducing limb fat<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Adipose tissue morphology improved after treatment discontinuation\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/2996\">Adipose tissue morphology improved after treatment discontinuation<\/a><\/li>\n<\/ul>\n<ul>\n<li><a title=\"Permanent link to Incidence of lipodystrophy in Rwanda\" rel=\"bookmark\" href=\"https:\/\/i-base.info\/htb\/2994\">Incidence of lipodystrophy in Rwanda<\/a><\/li>\n<\/ul>\n<p> This annual Workshop is the most important meeting for researchers, clinicians      and advocates who focus on metabolic complications relating to management      of HIV-positive patients.<\/p>\n<p>While many studies reaffirmed the role of some ARVs in risk factors associated      with lipodystrophy, cardiovascular disease and diabetes, there was further      evidence on managing this risk by treatment choice. While lipoatrophy is now      firmly linked to use of thymidine analogues and some degree of fat reversal      occurs when switching to alternative drugs, notably tenofovir or abacavir,      the mechanism to reverse fat accumulation is less clear.<\/p>\n<p>Research into lipodystrophy over the last few years has increasingly focused      on understanding adipogenesis as a dynamic process, and on the role of two      major proteins produced by adipocytes: leptin and adiponectin, which act as      hormones in their effect on different organs. At this years workshop, the      role of inflammation by macrophage and lymphocyte activity in adipose tissue      was also shown to be an increasingly important factor.<\/p>\n<p>Although an interesting study suggested that leptin may be a useful treatment      for reducing central fat accumulation, this research has been slow and leptin      isn\u0092t a clinical option at the moment. Prevention, through choice of      initial treatment, switching treatment when necessary and lifestyle modification,      was still stressed as the take-home message.<\/p>\n<p>Clinical discussions included the role of the metabolic syndrome, and the      high incidence of risk factors for insulin resistance and progression to type-2      diabetes in patients with HIV &#8211; and the degree to which this risk is underestimated.<\/p>\n<p>For the first time, the organisers of the meeting have produced webcasts      of many of the key presentations and discussions. This is a very positive      and important step towards making medical research presented at the workshop      available to a wider audience. Abstracts from the meeting together with webcasts      of oral sessions and some slide presentations are posted on the conference      website:<\/p>\n<p><a href=\"http:\/\/www.intmedpress.com\/lipodystrophy\">http:\/\/www.intmedpress.com\/lipodystrophy<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reports from the workshop The role of the metabolic syndrome in HIV Effect of lifestyle modification on risk factors for cardiovascular disease and metabolic syndrome Pioglitazone reduces peripheral lipoatrophy and improves adipokines without reducing visceral fat Leptin reduces visceral abdominal &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[12,129],"class_list":["post-3025","post","type-post","status-publish","format-standard","hentry","category-conference-reports","tag-conference-index","tag-lipo-8th-2006"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/3025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=3025"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/3025\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=3025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=3025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=3025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}