{"id":336,"date":"2008-12-27T08:33:22","date_gmt":"2008-12-27T07:33:22","guid":{"rendered":"http:\/\/localhost\/new\/htb\/?p=336"},"modified":"2013-08-23T12:46:07","modified_gmt":"2013-08-23T12:46:07","slug":"course-of-labour-in-pregnant-hiv-positive-women-with-no-contraindication-for-vaginal-delivery","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/336","title":{"rendered":"Course of labour in pregnant HIV-positive women with no contraindication for vaginal delivery"},"content":{"rendered":"<p><strong>Polly Clayden, HIV i-Base<\/strong><\/p>\n<p><strong>A French study found that the course of labour in HIV-positive women receiving ART with no contraindication (neither obstetrical nor virological) for vaginal delivery was similar to that of HIV-negative women.<\/strong><\/p>\n<p>This was a case-control study conducted between January 2000 and December 2005 in a single centre. Cases were matched with controls for parity, previous cesarean delivery and geographical origin.<\/p>\n<p>The investigators reported no difference in the course of labour or the foetal tolerance of labor among the146 cases included in the analysis and matched with HIV-negative controls.<\/p>\n<p>There was no difference in Caesarean delivery and assisted vaginal delivery rates were not different between the HIV-positive and negative women. The rate of episiotomy was significantly lower in HIV-positive women in this analysis (29.6% vs. 45.6%, p= 0.01) with no difference in the mean neonatal weight or the perineal laceration rate (simple or complex). They also found no difference in neonatal outcome.<\/p>\n<p>In the HIV-positive group there were no cases of mother-to-child transmission.<\/p>\n<p>Post-partum morbidity was similar between the groups. But the investigators noted that in HIV-positive women post-partum morbidity was significantly higher in women with CD4 count &lt;200 cells\/mm3 to &gt;200 cells\/mm3 (22.2% vs. 3.2%, p=0.007).<\/p>\n<p>Reference:<\/p>\n<p>Azria E, Kahn A, Schmitz T et al. Course of labour in HIV infected pregnant women with no contraindication for vaginal delivery. 48th ICAAC, 25-28 October 2008. Washington. Abstract H-454.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Polly Clayden, HIV i-Base A French study found that the course of labour in HIV-positive women receiving ART with no contraindication (neither obstetrical nor virological) for vaginal delivery was similar to that of HIV-negative women. This was a case-control study &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,35],"tags":[102],"class_list":["post-336","post","type-post","status-publish","format-standard","hentry","category-conference-reports","category-pmtct-and-maternal-health","tag-icaac-48th-2008"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/336","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=336"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/336\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}