{"id":35315,"date":"2018-11-13T11:16:59","date_gmt":"2018-11-13T11:16:59","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=35315"},"modified":"2018-11-13T16:15:47","modified_gmt":"2018-11-13T16:15:47","slug":"eacs-guidelines-version-9-1-update-2018","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/35315","title":{"rendered":"EACS guidelines &#8211; version 9.1 update (2018)"},"content":{"rendered":"<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright  wp-image-35316\" src=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2018\/11\/EACS-guidelines-v9.1-cover-212x300.png\" alt=\"\" width=\"173\" height=\"241\" \/>Simon Collins, HIV i-Base<\/strong><\/p>\n<p><strong>The 2018 update to the European guidelines for treatment of HIV-positive adults in Europe is now available online and as a PDF file.<span class=\"Apple-converted-space\">\u00a0<\/span><\/strong><\/p>\n<p>Currently, online the English edition &#8211; version 9.1 &#8211; is available but translations into additional languages will be published later as they become available.<\/p>\n<p>These include Chinese, French, German, Portuguese, Russian Spanish and Japanese (currently online as version 9.0 from 2017).<\/p>\n<p>The changes to the 2018 edition are also helpfully summarised on the first page.<\/p>\n<p>These include:<\/p>\n<ul>\n<li>Adopting integrase inhibitor-based ART (but not elvitegravir) as first-line therapy, although boosted darunavir is also included as preferred option.<\/li>\n<li>Downgrading elvitegravir to an alternative option.<\/li>\n<li>Including recently approved drugs like bictegravir, TAF and once-daily raltegravir.<\/li>\n<li>Including the two-drug combination of dolutegravir + lamivudine as an alternative option (if viral load is &lt;500,000)<\/li>\n<li>Dolutegravir (during first trimester), raltegravir 1200 mg, bictegravir, and darunavir\/cobicistat are no longer recommended during pregnancy.<\/li>\n<li>Drug interactions have been included for newer drugs.<\/li>\n<li>Smaller changes have also been made to the sections on management of TB, hepatitis and other opportunistic infections.<\/li>\n<\/ul>\n<p>Links<\/p>\n<p>EACS guidelines (2018)<br \/>\n<a href=\"http:\/\/www.eacsociety.org\/guidelines\/eacs-guidelines\/eacs-guidelines.html\">www.eacsociety.org\/guidelines\/eacs-guidelines\/eacs-guidelines.html<\/a> \u00a0<a href=\"http:\/\/www.eacsociety.org\/files\/2018_guidelines-9.1-english.pdf\" rel=\"noopener\">www.eacsociety.org\/files\/2018_guidelines-9.1-english.pdf<\/a> (PDF)<\/p>\n<p>Summary of changes from v 9.0 to v 9.1 editions.<br \/>\n<a href=\"http:\/\/www.eacsociety.org\/files\/guidelines_changes_from_v9.0_to_v9.1.pdf\" rel=\"noopener\">www.eacsociety.org\/files\/guidelines_changes_from_v9.0_to_v9.1.pdf<\/a> (PDF)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base The 2018 update to the European guidelines for treatment of HIV-positive adults in Europe is now available online and as a PDF file.\u00a0 Currently, online the English edition &#8211; version 9.1 &#8211; is available but translations &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[],"class_list":["post-35315","post","type-post","status-publish","format-standard","hentry","category-guidelines"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/35315","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=35315"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/35315\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=35315"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=35315"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=35315"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}