{"id":36595,"date":"2019-08-23T09:00:15","date_gmt":"2019-08-23T09:00:15","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=36595"},"modified":"2019-12-06T09:59:08","modified_gmt":"2019-12-06T09:59:08","slug":"htb-23-august-2019-online-second-reports-from-ias-2019","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/36595","title":{"rendered":"HTB 23 August 2019 online: second reports from IAS 2019"},"content":{"rendered":"<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-36338\" src=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2019\/07\/IAS-2019-web-logo-text-176x300.png\" alt=\"\" width=\"176\" height=\"300\" srcset=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2019\/07\/IAS-2019-web-logo-text-176x300.png 176w, https:\/\/i-base.info\/htb\/wp-content\/uploads\/2019\/07\/IAS-2019-web-logo-text.png 237w\" sizes=\"auto, (max-width: 176px) 100vw, 176px\" \/><\/span><\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/i-base.info\/htb\/date\/2019\/08\" rel=\"noopener noreferrer\">Contents online<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2019\/08\/HTB-23-Aug-2019-no-10-2-column.pdf\" rel=\"noopener noreferrer\">PDF of this issue<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/forms\/esub.php\">Subscribe by email<\/a><\/li>\n<\/ul>\n<p><strong>This bank holiday edition of HTB continues with further reports from the IAS 2019 conference held in Mexico City from 21 &#8211; 24 July.<\/strong><\/p>\n<p>These include several important studies on ART strategies.<\/p>\n<p>Importantly, we highlight that reduced dosing (4 vs 7 days a week) are NOT equivilent options due to the risk of serious drug resistance with some combinations.<\/p>\n<p>We also report the unexpected association of weight gain with dolutegravir in the randomised South African ADVANCE study.<\/p>\n<p>Other reports on integrase inhibitors include use of dolutegravir in younger children in Odessey study and a review of several studies reporting high efficacy of switching to bictegravir\/F\/TAF, with analyses for drug resistance.<\/p>\n<p>We also include on the PK analysis from the DISCOVER study that reports on potential advantages of F\/TAF for PrEP in people with low adherence.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Second reports from IAS 2019&#8230;<\/p>\n","protected":false},"author":3,"featured_media":36799,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-36595","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editorial"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/36595","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=36595"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/36595\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media\/36799"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=36595"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=36595"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=36595"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}