{"id":37431,"date":"2020-03-27T11:32:47","date_gmt":"2020-03-27T11:32:47","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=37431"},"modified":"2020-05-15T10:22:08","modified_gmt":"2020-05-15T10:22:08","slug":"covid-19-is-associated-with-significant-drops-in-cd4-count","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/37431","title":{"rendered":"COVID-19 is associated with significant drops in CD4 count"},"content":{"rendered":"<p class=\"HTBsubhead3authorcredit\"><strong><span lang=\"EN-US\"><img loading=\"lazy\" decoding=\"async\" class=\" alignright\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2020\/03\/COVID-19-graphic.png\" width=\"231\" height=\"142\" \/>Simon Collins, HIV i-Base<\/span><\/strong><\/p>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\">The paper describes lab results including peripheral lymphocyte subsets in 452 people with COVID-19 in China, 286 of them had severe disease. Median age was 58 with roughly half men and half women.<\/span><\/strong><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">The abstract reports the most common symptoms were fever, shortness of breath, expectoration, fatigue, dry cough and myalgia. Severe cases tended to have lower lymphocytes counts, higher leukocytes counts and neutrophil-lymphocyte-ratio (NLR), and lower percentages of monocytes, eosinophils, and basophils.<\/span><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Severe cases also had higher infection-related biomarkers and inflammatory cytokines.<\/span><\/p>\n<p class=\"HTBreference-noindent\"><span lang=\"EN-US\">Ref: Qin C et al. Dysregulation of immune response in patients with COVID-19 in Wuhan, China<span class=\"apple-converted-space\">.<\/span> <\/span><span lang=\"EN-US\">Clinical Infectious Diseases<\/span><span lang=\"EN-US\">,<\/span><span lang=\"EN-US\"> ciaa248. (12 March 2020). DOI: 10.1093\/cid\/ciaa248<br \/>\n<\/span><a href=\"https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciaa248\/5803306\" rel=\"noopener noreferrer\"><span lang=\"EN-US\">https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciaa248\/5803306<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base The paper describes lab results including peripheral lymphocyte subsets in 452 people with COVID-19 in China, 286 of them had severe disease. Median age was 58 with roughly half men and half women. The abstract reports &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[290,278],"tags":[],"class_list":["post-37431","post","type-post","status-publish","format-standard","hentry","category-covid-19-pathogenesis","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/37431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=37431"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/37431\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=37431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=37431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=37431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}