{"id":37912,"date":"2020-05-14T08:10:01","date_gmt":"2020-05-14T08:10:01","guid":{"rendered":"http:\/\/i-base.info\/htb\/?p=37912"},"modified":"2020-05-15T16:27:49","modified_gmt":"2020-05-15T16:27:49","slug":"reviews-of-immunology-of-covid-19","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/37912","title":{"rendered":"Reviews on immunology of COVID-19"},"content":{"rendered":"<p class=\"HTBsubhead3authorcredit\"><strong><span lang=\"EN-US\"><b><img loading=\"lazy\" decoding=\"async\" class=\" alignright\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2020\/03\/COVID-19-graphic.png\" width=\"231\" height=\"142\" \/><\/b>Simon Collins, HIV i-Base<\/span><\/strong><\/p>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\">The following two reviews are useful overviews on current approaches to understanding immunology of COVID-19.<\/span><\/strong><\/p>\n<p class=\"HTBBODYtext\"><b><span lang=\"EN-US\">Immunology of COVID-19: current state of the science. Immunity (2020).<br \/>\n<\/span><\/b><span lang=\"EN-US\">Vabret N et al. j.immuni.2020.05.002. DOI: 10.1016\/j.immuni.2020.05.002<br \/>\n<\/span><a href=\"https:\/\/www.cell.com\/action\/showPdf?pii=S1074-7613%2820%2930183-7\" rel=\"noopener noreferrer\"><span lang=\"EN-US\">https:\/\/www.cell.com\/action\/showPdf?pii=S1074-7613%2820%2930183-7<\/span><\/a><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">This review summarise the current state of knowledge of innate and adaptive immune responses from SARS-CoV-2 and the immunological pathways that are likely to contribute to disease severity and death. <\/span><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">It also discusses the rationale and clinical outcome of current approaches to treatment and is sufficiently updated to include all recent remdesivir studies. It also reviews some of the prospective clinical trials to prevent or treat SARS-CoV-2 infection. <\/span><\/p>\n<p class=\"HTBBODYtext\"><b><span lang=\"EN-US\">The many faces of the anti-COVID immune response.<br \/>\n<\/span><\/b><span lang=\"EN-US\">Vardhana SA et al. JEM, 216(6) (30 April 2020).<br \/>\n<\/span><a href=\"https:\/\/rupress.org\/jem\/article-standard\/217\/6\/e20200678\/151725\/The-many-faces-of-the-anti-COVID-immune-responseA\" rel=\"noopener noreferrer\"><span lang=\"EN-US\">https:\/\/rupress.org\/jem\/article-standard\/217\/6\/e20200678\/151725\/The-many-faces-of-the-anti-COVID-immune-responseA<\/span><\/a><\/p>\n<p>A review of active vs innate immune activation and COVID-19, that also cautions about this being an IL-6-mediated cytokine release syndrome.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base The following two reviews are useful overviews on current approaches to understanding immunology of COVID-19. Immunology of COVID-19: current state of the science. Immunity (2020). Vabret N et al. j.immuni.2020.05.002. DOI: 10.1016\/j.immuni.2020.05.002 https:\/\/www.cell.com\/action\/showPdf?pii=S1074-7613%2820%2930183-7 This review summarise &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[287,278],"tags":[],"class_list":["post-37912","post","type-post","status-publish","format-standard","hentry","category-covid-19-on-the-web","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/37912","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=37912"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/37912\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=37912"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=37912"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=37912"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}