{"id":38551,"date":"2020-07-22T07:30:05","date_gmt":"2020-07-22T07:30:05","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=38551"},"modified":"2020-07-29T15:29:16","modified_gmt":"2020-07-29T15:29:16","slug":"nyc-cohort-reports-similar-outcomes-from-covid-19-in-hiv-positive-vs-hiv-negative-adults","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/38551","title":{"rendered":"NYC cohort reports similar outcomes from COVID-19 in HIV positive vs HIV negative adults"},"content":{"rendered":"

Simon Collins, HIV i-Base<\/span><\/strong><\/p>\n

A retrospective case-control analysis of outcomes from COVID-19 reports similar outcomes for 88 HIV positive adults in New York compared to HIV negative people. [1]<\/span><\/strong><\/p>\n

Of the 4,402 adults hospitalised at five clinics between 12 March and 23 April 2020, 88 were HIV positive (2%). Median age of HIV positive group was 61 years (IQR: 54 to 67) and most were black (40%) or Hispanic\/Latino (30%). Cases were then matched to controls (1:5) by age, sex or race\/ethnicity. <\/span><\/p>\n

Significant differences that still remained however including a higher proportion of smokers in the HIV positive group (55% vs 23%, p<0.001) and more comorbidities (compared to matched controls). These included <\/span>COPD (10% vs 3%, p<0.001),\u00a0cirrhosis (6% vs 2%, p=0.02)\u00a0and a\u00a0history of cancer (17% vs 6%, p=0.001).<\/p>\n

All HIV positive people were on ART (78% INSTI-based) with 81% having recent undetectable viral load. However, only 58% had a CD4 count >200 cells\/mm3\u00a0<\/sup>and CD4% was generally reduced compared to most recent pre-admission test (median decline \u20134% (IQR: 0 to 9%).<\/span><\/p>\n

Compared to controls, the study reported no differences by HIV status in key outcomes. Severity of COVID-19 on admission (measured by need for oxygen) was similar (p=0.15). Although poor outcomes after hospitalisation were frequent, they were also similar in each group. Overall, 18% vs 23% required mechanical ventilation and 21% vs 20% died, in the positive vs negative groups respectively. <\/span><\/p>\n

The study reported a similar cumulative incidence of death over time by HIV status (p=0.94).<\/span><\/p>\n

Reference<\/span><\/p>\n

    \n
  1. Sigel K et al. Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients in New York City. Clinical Infectious Diseases, ciaa880,\u00a0DOI: 10.1093\/cid\/ciaa880. \u00a0(28 June 2020).
    \n<\/span>https:\/\/academic.oup.com\/cid\/article\/doi\/10.1093\/cid\/ciaa880\/5864410<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Simon Collins, HIV i-Base A retrospective case-control analysis of outcomes from COVID-19 reports similar outcomes for 88 HIV positive adults in New York compared to HIV negative people. [1] Of the 4,402 adults hospitalised at five clinics between 12 March …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282,278],"tags":[],"class_list":["post-38551","post","type-post","status-publish","format-standard","hentry","category-covid-19-hiv-and-covid-19-coinfection","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/38551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=38551"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/38551\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=38551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=38551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=38551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}