{"id":39628,"date":"2021-01-22T07:29:47","date_gmt":"2021-01-22T07:29:47","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=39628"},"modified":"2021-01-26T13:24:58","modified_gmt":"2021-01-26T13:24:58","slug":"very-low-level-viral-load-viraemia-might-continue-after-covid-19","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/39628","title":{"rendered":"Very low-level HIV viraemia might continue after COVID-19"},"content":{"rendered":"
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<\/span><\/b>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n

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A letter to CID reported a concern that higher HIV viral load levels might occur after HIV positive people on ART have recovered from COVID-19. However no significant differences were observed and no blips were reported above 20 copies\/mL.<\/span><\/strong><\/p>\n<\/div>\n

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The results were from testing large volumes of HIV plasma using single copy viral load tests in 12 HIV positive people a median of 37 days (IQR: 29 to 62) after first COVID-19 symptoms compared to a control group of 17 HIV positive people the previous year. <\/span><\/p>\n<\/div>\n

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Although not statistically significant, more people had detectable viral load in the COVID group: 83% vs 59%, whereas other characteristics were closely matched. The median viral load was also slightly higher: 1.59 \u00a0vs 0.38 copies\/mL in people with recent COVID-19 vs historical control.<\/span><\/p>\n<\/div>\n

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Four of the COVID group had subsequent testing a median of 75 days (IQR: 58 to 90 days) with 3\/4 still showing detectable viral load: median, 1.95 copies\/mL (IQR: 0.1 to 14.53).<\/span><\/p>\n<\/div>\n

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It is reassuring that the differences were small and without likely clinical significance. However, the low sample size suggest that larger studies are needed to know whether or not post-COVID viraemia might be a real effect.<\/span><\/p>\n<\/div>\n

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Reference<\/span><\/p>\n<\/div>\n

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Peluso MJ et al. A high percentage of people with HIV on antiretroviral therapy experience detectable low-level plasma HIV-1 RNA following COVID-19. Clinical Infectious Diseases, ciaa1754, DOI:10.1093\/cid\/ciaa1754. (19 November 2020).
\n<\/span>https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciaa1754\/5991913<\/a><\/p>\n

This report was first posted on 5 January 2021.<\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Simon Collins, HIV i-Base A letter to CID reported a concern that higher HIV viral load levels might occur after HIV positive people on ART have recovered from COVID-19. However no significant differences were observed and no blips were reported …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282,290,278],"tags":[],"class_list":["post-39628","post","type-post","status-publish","format-standard","hentry","category-covid-19-hiv-and-covid-19-coinfection","category-covid-19-pathogenesis","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/39628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=39628"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/39628\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=39628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=39628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=39628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}