![\"\"](\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2021\/05\/HTB-5-May-2021-cover-211x300.png\")
<\/p>\n<\/p>\n
This issue of HTB starts by remembering Paul Decle, a UK community activist who was part of the core group that founded i-Base in April 2000, and who supported many other UK organisations.<\/strong><\/p>\n And although we planned to steadily reduce our coverage of COVID-19, the first reports from the 5th BHIVA\/BASHH conference, all report on outcomes in people living with HIV.<\/p>\n These include results from a BHIVA audit and from a PHE analysis, both reporting HIV as an independent risk for worse outcomes.<\/p>\n Our reports include the publication of NICE guidelines on pain management and the news that the UK government plans to reduce funding to UNAIDS by 80%.<\/p>\n And then we roll into 15 reports related to COVID-19, ranging from vaccines research, experimental treatment, long COVID, transmission and prevention.<\/p>\n Of these, perhaps the most serious, reports significantly reduced immune response to the full course of mRNA vaccines in populations with immune suppression. For example, 30% of participants older than 80 years and 50% of recipients of solid organ transplant produced no detectable immune response, three weeks after the second dose.<\/p>\n This raises important questions for some HIV positive people who are in either of these groups, or who are more vulnerable due to BHIVA criteria of having a very low CD4 count (<50 or perhaps <200 cells\/mm3<\/sup>).<\/p>\n Until supported by evidence of protection, either on an individual or subgroup level, it might not be accurate to rely on immune protection after a coompleted vaccine schedule.\u00a0<\/span><\/p>\n But with so much to read, we will keep this introduction short.<\/p>\n Happy reading.<\/p>\n\n","protected":false},"excerpt":{"rendered":" Paul Decle, 5th BHIVA\/BASHH conference, NICE pain guidelines plus 15 COVID-19 reports…<\/p>\n","protected":false},"author":3,"featured_media":40603,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,9],"tags":[],"class_list":["post-40555","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editorial","category-special-reports"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=40555"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40555\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media\/40603"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=40555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=40555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=40555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}