{"id":40667,"date":"2021-06-01T07:17:51","date_gmt":"2021-06-01T07:17:51","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=40667"},"modified":"2021-06-01T08:52:36","modified_gmt":"2021-06-01T08:52:36","slug":"correlation-between-covid-19-severity-and-immune-responses-after-six-months","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/40667","title":{"rendered":"Correlation between COVID-19 severity and immune responses after six months"},"content":{"rendered":"<div>\n<p class=\"HTBsubhead2articletitle\"><strong><span lang=\"EN-US\"><img loading=\"lazy\" decoding=\"async\" class=\" alignright\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2020\/03\/COVID-19-graphic.png\" width=\"231\" height=\"142\" \/><\/span>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\">The strength and durability of immune responses after recovery from COVID-19 helps model the future public health risks and can also inform the timing of vaccination.<\/span><\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">This study reports the duration of humoral and cellular immunity in 97 participants from three stages: asymptomatic (n=14), symptomatic\/non-pneumonic (n=42), and pneumonic (n=41).<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Six months after diagnosis, overall anti-SARS-CoV-2 IgG and neutralising antibody (NAb) titers were positive in 66.7% and 86.9%,\u00a0<\/span>in the combined non-pneumonic<span class=\"Apple-converted-space\">\u00a0<\/span>and pneumonic groups respectively.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">respectively. Those with this sustained humoral immunity were more likely to be older, with longer viral shedding and pneumonia &#8211; and were also more likely to have a SARC-CoV-2 specific T-cell response.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBreference-noindent\"><span lang=\"EN-US\">Reference<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBreference-noindent\"><span lang=\"EN-US\">Noh JY et al. Longitudinal assessment of anti-SARS-CoV-2 immune responses for six months based on the clinical severity of COVID-19<i>. <\/i>JID, jiab124,\u00a0DOI: 10.1093\/infdis\/jiab124. (4 March 2021).<br \/>\n<\/span><a href=\"https:\/\/academic.oup.com\/jid\/advance-article\/doi\/10.1093\/infdis\/jiab124\/6158870\">https:\/\/academic.oup.com\/jid\/advance-article\/doi\/10.1093\/infdis\/jiab124\/6158870<\/a><\/p>\n<p><em>This report was first published on 17 May 2020.<\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base The strength and durability of immune responses after recovery from COVID-19 helps model the future public health risks and can also inform the timing of vaccination. This study reports the duration of humoral and cellular immunity &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[290,289,278],"tags":[],"class_list":["post-40667","post","type-post","status-publish","format-standard","hentry","category-covid-19-pathogenesis","category-covid-19-transmission","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=40667"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40667\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=40667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=40667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=40667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}