{"id":40711,"date":"2021-06-01T07:32:41","date_gmt":"2021-06-01T07:32:41","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=40711"},"modified":"2021-06-01T08:46:46","modified_gmt":"2021-06-01T08:46:46","slug":"mhra-authorises-janssen-jj-covid-19-vaccination-in-the-uk","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/40711","title":{"rendered":"MHRA authorises Janssen\/J&J COVID-19 vaccination in the UK"},"content":{"rendered":"
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<\/span>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n

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On 28 May 2021, the UK Medicines and Healthcare products Regulatory Agency (MHRA) \u00a0authorised use of the Janssen\/J&J single-dose (Ad26-COV2.S) vaccine against COVID-19. [1]<\/span><\/strong><\/p>\n<\/div>\n

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This is based on top-line efficacy rates of<\/span>67% overall in preventing COVID-19 infection. After two weeks there were 116 vs 348 cases in the active vs placebo arms respectively, out of almost 20,000 people in each arm. The vaccine was <\/span>85% effective in preventing severe disease or hospitalisation.<\/p>\n<\/div>\n

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Although the vaccine only needs a single dose ongoing studies are looking at using two doses. The vaccine can be transported and stored for up to three months at regular fridge temperatures (2 to 8 C). It is a DNA-based vaccine delivered using inactivated adenovirus-26.<\/p>\n<\/div>\n

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The UK has apparently reduced the original 30 million doses ordered to 20 million doses although the vaccine will not be available until later in the year.<\/p>\n<\/div>\n

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The European Medicines Agency (EMA) recommended authorisation in the EU in March 2021. [2]<\/span><\/p>\n<\/div>\n

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Reference<\/span><\/p>\n<\/div>\n

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  1. Gov.uk. Press release. Janssen coronavirus (COVID-19) vaccine authorised by UK medicines regulator. (28 May 2021).
    \n<\/span>https:\/\/www.gov.uk\/government\/news\/janssen-coronavirus-covid-19-vaccine-authorised-by-uk-medicines-regulator<\/a><\/li>\n
  2. EMA. EMA recommends COVID-19 Vaccine Janssen for authorisation in the EU. (11 March 2021).
    \n    https:\/\/www.ema.europa.eu\/en\/news\/ema-recommends-covid-19-vaccine-janssen-authorisation-eu<\/a><\/li>\n<\/ol>\n

    This report was first published on 28 May 2021.<\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Simon Collins, HIV i-Base On 28 May 2021, the UK Medicines and Healthcare products Regulatory Agency (MHRA) \u00a0authorised use of the Janssen\/J&J single-dose (Ad26-COV2.S) vaccine against COVID-19. [1] This is based on top-line efficacy rates of67% overall in preventing COVID-19 …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[292,278],"tags":[],"class_list":["post-40711","post","type-post","status-publish","format-standard","hentry","category-covid-19-vaccine","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40711","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=40711"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40711\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=40711"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=40711"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=40711"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}