{"id":40851,"date":"2021-07-01T06:35:44","date_gmt":"2021-07-01T06:35:44","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=40851"},"modified":"2021-07-17T09:42:39","modified_gmt":"2021-07-17T09:42:39","slug":"london-hiv-study-to-look-at-responses-to-covid-19-vaccines-and-natural-infection","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/40851","title":{"rendered":"London HIV study of responses to COVID-19 vaccines and natural infection (SCAPE)"},"content":{"rendered":"
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Simon Collins, HIV i-Base<\/span><\/strong><\/p>\n<\/div>\n

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A study enrolling at the Royal Free Hospital (RFH) in London is looking to look at immune responses to SARS-CoV-2 in people living with HIV. [1]<\/span><\/strong><\/p>\n<\/div>\n

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This will include responses both to natural infection and to vaccinations against COVID-19.<\/span><\/p>\n<\/div>\n

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The results will help understand how HIV affects risk for COVID-19 and whether alternative vaccines strategies are needed for some HIV positive people.<\/span><\/p>\n<\/div>\n

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The study involves one additional blood sample, with additional samples dependent on the initial results together with a questionnaire on COVID risk. <\/span><\/p>\n<\/div>\n

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The study is being run by Dr Tristan Barber and is open to all HIV positive people whose HIV care is at the RFH. [2]<\/span><\/p>\n<\/div>\n

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comment<\/span><\/h3>\n<\/div>\n
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This is an easy study to recommend.<\/span><\/strong><\/p>\n<\/div>\n

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Currently there is very limited data in HIV positive people and this is generally only in people with high CD4 counts and undetectable viral load on ART.<\/span><\/strong><\/p>\n<\/div>\n

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There are increasing reports of limited vaccine responses in people with significant immune suppression without clear guidelines for managing care in this situation.<\/span><\/strong><\/p>\n<\/div>\n

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References<\/span><\/p>\n<\/div>\n

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  1. SARS CoV-2 antibody prevalence in an adult HIV cohort (SCAPE-HIV Study). IRAS ID 290112. (Note this listing needs updating).
    \n<\/span>https:\/\/www.hra.nhs.uk\/planning-and-improving-research\/application-summaries\/research-summaries\/scape-hiv<\/a><\/li>\n
  2. Contact for the research team is <\/span>020 7472 6232.<\/li>\n<\/ol>\n<\/div>\n
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    \u00a0<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Simon Collins, HIV i-Base A study enrolling at the Royal Free Hospital (RFH) in London is looking to look at immune responses to SARS-CoV-2 in people living with HIV. [1] This will include responses both to natural infection and to …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282,292,288,278],"tags":[],"class_list":["post-40851","post","type-post","status-publish","format-standard","hentry","category-covid-19-hiv-and-covid-19-coinfection","category-covid-19-vaccine","category-covid-19-research-studies","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40851","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=40851"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40851\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=40851"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=40851"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=40851"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}