{"id":40880,"date":"2021-07-01T06:25:18","date_gmt":"2021-07-01T06:25:18","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=40880"},"modified":"2021-07-01T07:21:12","modified_gmt":"2021-07-01T07:21:12","slug":"research-approach-to-rapidly-review-candidate-treatments-for-covid-19-nine-studies-using-activ-protocol","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/40880","title":{"rendered":"Research approach to rapidly review candidate treatments for COVID-19: nine studies using ACTIV protocol"},"content":{"rendered":"<div>\n<p class=\"HTBsubhead2articletitle\"><strong><span lang=\"EN-US\"><img loading=\"lazy\" decoding=\"async\" class=\" alignright\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2020\/03\/COVID-19-graphic.png\" width=\"231\" height=\"142\" \/><\/span>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\">This paper outlines a research approach to the urgency needed for medicines to treat COVID-19.<\/span><\/strong><\/p>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">This includes a rapid early review of results, with early stopping rules, that limits the risk of extended exposure to inactive treatments.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">The overall programme includes master protocols for interventions for prevention and treatment at different stages.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Reference<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Lavange L et al. Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): Designing Master Protocols for Evaluation of Candidate COVID-19 Therapeutics. A<\/span>nn Int Med. DOI: 10.7326\/M21-1269 (29 June 2021).<br \/>\n<a href=\"https:\/\/www.acpjournals.org\/doi\/10.7326\/M21-1269\">https:\/\/www.acpjournals.org\/doi\/10.7326\/M21-1269<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base This paper outlines a research approach to the urgency needed for medicines to treat COVID-19. This includes a rapid early review of results, with early stopping rules, that limits the risk of extended exposure to inactive &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283,288,278],"tags":[],"class_list":["post-40880","post","type-post","status-publish","format-standard","hentry","category-covid-19-investigational-drugs","category-covid-19-research-studies","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=40880"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/40880\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=40880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=40880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=40880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}