{"id":41433,"date":"2021-10-31T07:15:33","date_gmt":"2021-10-31T07:15:33","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=41433"},"modified":"2021-11-01T15:02:44","modified_gmt":"2021-11-01T15:02:44","slug":"sputnik-v-vaccine-not-approved-in-south-africa-due-to-concerns-about-increased-risk-of-hiv","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/41433","title":{"rendered":"Sputnik V vaccine not approved in South Africa due to potential increased risk of HIV"},"content":{"rendered":"
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<\/span>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n

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On 18 October 2021, after an eight-month review, the South African Health Products Regulatory Authority (SAPHRA) decided not to grant emergency use approval to the Sputnik V vaccine. [1]<\/span><\/strong><\/p>\n<\/div>\n

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This was due to lack of data proving safety in a population with high background of HIV infection.<\/span><\/p>\n<\/div>\n

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The concerns came from previous Ad-5 vector HIV vaccine studies (STEP and PHAMBILI) , that reported increased risk of HIV acquisition in uncircumcised heterosexual men. This issue was raised by other researchers in a letter to the Lancet in October 2020. [2]<\/span><\/p>\n<\/div>\n

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The Sputnik V vaccine was developed by the Gamaleya Research Institute of Epidemiology and Microbiology in the Russian Federation. It has also not received emergency use listing by the WHO.<\/span><\/p>\n<\/div>\n

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Namibia has also followed the South African decision by suspending use of the Sputnik V vaccine.<\/span><\/p>\n<\/div>\n

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References<\/span><\/p>\n<\/div>\n

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    \n
  1. SAHPRA <\/span>press release. Update on the <\/span>SAHPRA <\/span>review of the Sputnik V vaccine. (18 October 2021).
    \n<\/span>https:\/\/www.sahpra.org.za\/wp-content\/uploads\/2021\/10\/MEDIA-RELEASE-Sputnik-Vaccine_18Oct-2021.pdf<\/a> (PDF)<\/li>\n
  2. HIV risk from some COVID-19 vaccines might be unlikely due to rarity of vector viruses involved. HTB (December 2020).
    \n    https:\/\/i-base.info\/htb\/39455<\/a><\/li>\n
  3. Reuters. Namibia suspends use of Russian COVID vaccine after South Africa flags HIV concerns. (23 October 2021).
    \n    https:\/\/www.reuters.com\/world\/africa\/namibia-suspends-use-russian-covid-vaccine-after-safrica-flags-hiv-concerns-2021-10-23<\/span><\/a><\/li>\n<\/ol>\n

    The article was first posted on 23 October 2021.<\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Simon Collins, HIV i-Base On 18 October 2021, after an eight-month review, the South African Health Products Regulatory Authority (SAPHRA) decided not to grant emergency use approval to the Sputnik V vaccine. [1] This was due to lack of data …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[292,278],"tags":[],"class_list":["post-41433","post","type-post","status-publish","format-standard","hentry","category-covid-19-vaccine","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/41433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=41433"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/41433\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=41433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=41433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=41433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}