{"id":41766,"date":"2021-11-30T08:00:04","date_gmt":"2021-11-30T08:00:04","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=41766"},"modified":"2022-09-12T08:12:41","modified_gmt":"2022-09-12T08:12:41","slug":"htb-no-11-now-online-nov-dec-2021","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/41766","title":{"rendered":"HTB: no. 11 &#8211; plus HIV and COVID-19 (Nov\/Dec 2021)"},"content":{"rendered":"<ul>\n<li><a href=\"https:\/\/i-base.info\/htb\/date\/2021\/11\">Contents online<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2021\/11\/HIV-and-COVID-19-no-11-Nov-2021-1-column.pdf\">Download November 2021 &#8211; 1 column<\/a>\u00a0PDF file<\/li>\n<li><a href=\"https:\/\/i-base.info\/forms\/esub.php\">Subscribe to HTB by email<\/a><\/li>\n<\/ul>\n<p><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-41491\" src=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2021\/10\/logo2-300x284.png\" alt=\"\" width=\"229\" height=\"218\" srcset=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2021\/10\/logo2-300x284.png 300w, https:\/\/i-base.info\/htb\/wp-content\/uploads\/2021\/10\/logo2.png 454w\" sizes=\"auto, (max-width: 229px) 100vw, 229px\" \/>This issue contains <a href=\"https:\/\/i-base.info\/htb\/41723\">more coverage from the EACS 2021<\/a> conference held as a hybrid meeting in London last month.<\/strong><\/p>\n<p>We include the important news that <a href=\"https:\/\/i-base.info\/htb\/41623\">long-acting cabotegravir\/rilpivirine (CAB\/RPV-LA) injectable ART<\/a> has just been approved by NICE for use in England and Wales. This follows <a href=\"https:\/\/i-base.info\/htb\/41408\">approval in Scotland<\/a> last month.<\/p>\n<p>This is an important signal that new drugs will still be made available, even if they are more expensive that other current ART. Although actual drug prices are not public \u2013 only list prices are published in the BNF \u2013 CAB\/RPV-LA is likely to be close to higher priced non-generic combinations, such as Biktarvy (bictegravir\/F\/TAF). It will certainly be higher than combinations using generic ARVs.<\/p>\n<p>Unfortunately, we also include the disappointing news about the <a href=\"https:\/\/i-base.info\/htb\/41647\">stopped development of the NNRTI MK-8507<\/a>. This is due to unexpected reductions in total lymphocyte and CD4 counts. The press release also refers to a signal that something similar might be linked to islatravir. Other islatravir studies are all continuing \u2013 both for treatment and prevention \u2013 but with closer monitoring.<\/p>\n<p>Good news about a <a href=\"https:\/\/i-base.info\/htb\/41680\">new oral history project from CHIVA<\/a> for young people to record their experiences of living with HIV from birth.<\/p>\n<p>And just in time for World AIDS Day, news of the <a href=\"https:\/\/i-base.info\/htb\/41706\">third IAS report of a Global Scientific Strategy<\/a> to develop an HIV cure.\u00a0Published with open access in Nature Medicine, this comprehensive review covers more than 170 recent studies and is recommended reading.<\/p>\n<div>\n<p class=\"HTBBODYtext\">i-Base have posted an <a href=\"https:\/\/i-base.info\/ias-towards-an-hiv-cure-2021\">easy-to-read Q&amp;A version online that is less technical<\/a>. This will hopefully be a way for most people living with HIV to learn about exciting developments for a cure.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>News from EACS 2021, injectable ART in the UK, HIV cure research and more&#8230;<\/p>\n","protected":false},"author":3,"featured_media":41767,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-41766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editorial"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/41766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=41766"}],"version-history":[{"count":1,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/41766\/revisions"}],"predecessor-version":[{"id":44099,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/41766\/revisions\/44099"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media\/41767"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=41766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=41766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=41766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}