{"id":42734,"date":"2022-05-02T07:30:33","date_gmt":"2022-05-02T07:30:33","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=42734"},"modified":"2022-05-04T18:46:18","modified_gmt":"2022-05-04T18:46:18","slug":"asymptomatic-covid-19-is-common-in-people-living-with-hiv","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/42734","title":{"rendered":"Asymptomatic COVID-19 is common in people living with HIV"},"content":{"rendered":"<div>\n<p class=\"HTBsubhead2articletitle\"><strong>Simon Collins, HIV i-Base<\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\"><img loading=\"lazy\" decoding=\"async\" class=\" alignright\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2020\/03\/COVID-19-graphic.png\" width=\"231\" height=\"142\" \/><\/span>A sub-study in about one-third of participants in the international REPRIEVE trial reported COVID-19 infections from April 2020 in approximately 13%. Of these, roughly 60% were asymptomatic.<\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\">Overall,<span lang=\"EN-US\"> median age was 53 years, 35% were women, 47% Black or African American. The median CD4 count 649 cells\/mm<\/span><sup><span lang=\"EN-US\">3<\/span><\/sup><span lang=\"EN-US\">, and 97% with HIV undetectable viral load (&lt;400 copies\/mL). <\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Of the 2,464 participant included, 318 had either SARS-CoV-2 antibodies (260\/318), without previous vaccination and 58\/318 had were diagnosed clinically.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">In a self-completed questionnaire, only 40% reported symptoms. These rates were lower rates in low and middle income countries, in Black or African American race, older in age, and with higher ASCVD risk score.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">Symptoms were more common with obesity, metabolic syndrome, and low HDL levels. <\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">There was no association by CD4 counts and HIV viral load.<\/span><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\">Reference<\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\">Overton ET et al. Asymptomatic SARS-CoV-2 infection is common among ART-treated people with HIV, JAIDS Journal of Acquired Immune Deficiency Syndromes: &#8211; Volume &#8211; Issue &#8211; 10.1097\/QAI.0000000000003000 doi: 10.1097\/QAI.0000000000003000. (12 April 2022).<br \/>\n<a href=\"https:\/\/journals.lww.com\/jaids\/Abstract\/9900\/Asymptomatic_SARS_CoV_2_Infection_is_Common_among.27.aspx\">https:\/\/journals.lww.com\/jaids\/Abstract\/9900\/Asymptomatic_SARS_CoV_2_Infection_is_Common_among.27.aspx<\/a><\/p>\n<\/div>\n<p><em>This report was first published on 17 April 2022.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base A sub-study in about one-third of participants in the international REPRIEVE trial reported COVID-19 infections from April 2020 in approximately 13%. Of these, roughly 60% were asymptomatic. Overall, median age was 53 years, 35% were women, &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31,282,278],"tags":[],"class_list":["post-42734","post","type-post","status-publish","format-standard","hentry","category-opportunistic-infections-coinfections-and-complications","category-covid-19-hiv-and-covid-19-coinfection","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/42734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=42734"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/42734\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=42734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=42734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=42734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}