{"id":43737,"date":"2022-08-18T13:09:47","date_gmt":"2022-08-18T13:09:47","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=43737"},"modified":"2022-09-10T07:25:34","modified_gmt":"2022-09-10T07:25:34","slug":"bhiva-include-efficacy-data-on-hiv-and-monkeypox-vaccine-updated-statement","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/43737","title":{"rendered":"BHIVA include efficacy data on HIV and monkeypox vaccine: updated statement"},"content":{"rendered":"

Simon Collins, HIV i-Base<\/strong><\/p>\n

\"\"
\nOn 17 August 2022, BHIVA issued an updated statement on monkeypox (MPX) that includes information about vaccine efficacy, including in people living with HIV. [1]<\/strong><\/p>\n

The statement summarises information about the time to develop antibody responses and that these continue to increase over four weeks after a single shot.<\/p>\n

One of the two HIV studies includes that responses might be slightly lower and take longer to develop in people who are HIV positive compared to HIV negative.<\/p>\n

Importantly, it recommends that people living with HIV should receive two shots of the vaccine, even though it might take several months before the second dose.<\/p>\n

When available, people who currently have a CD4 count <200 cells\/mm3 should be prioritised for the second dose.<\/p>\n

Childhood vaccination against smallpox generates higher responses to a single vaccine shot.<\/p>\n

However, there is no evidence that the residual antibodies will prevent MPX infection now \u2013 10% of cases in a recent report had received the smallpox vaccine as a child. [2]<\/p>\n

comment<\/h3>\n

This update provides information that people can use when deciding their own levels of risk when returning to regular life.<\/strong><\/p>\n

This is especially important given the limited access to vaccines and that further supplies in the UK are not expected for 1\u20132 months.<\/strong><\/p>\n

Many people have already reduced their risk of exposure to MPX by changing how and when they have sex, given that this is only likely to be for a limited time, until vaccines become more widely available.<\/strong><\/p>\n

References<\/p>\n

    \n
  1. BHIVA rapid guidance on monkeypox virus. (Updated 17 August 2022).
    \nhttps:\/\/www.bhiva.org\/BHIVA-rapid-guidance-on-monkeypox-virus<\/a><\/li>\n
  2. International study of 528 monkeypox (MPX) cases: results from the 2022 outbreak need to inform new management guidelines. HTB (3 August 2022).
    \n    https:\/\/i-base.info\/htb\/43458<\/a><\/li>\n
  3. Collins S. Taking a break from monkeypox: four weeks out for August. HTB (3 August 2022).
    \n    https:\/\/i-base.info\/htb\/43686<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Simon Collins, HIV i-Base On 17 August 2022, BHIVA issued an updated statement on monkeypox (MPX) that includes information about vaccine efficacy, including in people living with HIV. [1] The statement summarises information about the time to develop antibody responses …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[323,31],"tags":[],"class_list":["post-43737","post","type-post","status-publish","format-standard","hentry","category-mpox","category-opportunistic-infections-coinfections-and-complications"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/43737","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=43737"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/43737\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=43737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=43737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=43737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}