{"id":43768,"date":"2022-09-01T06:32:28","date_gmt":"2022-09-01T06:32:28","guid":{"rendered":"https:\/\/127.0.0.1\/htb\/?p=43768"},"modified":"2022-09-10T21:36:47","modified_gmt":"2022-09-10T21:36:47","slug":"bhiva-include-efficacy-data-on-hiv-and-monkeypox-vaccine-updated-statement-august-2022","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/43768","title":{"rendered":"BHIVA include efficacy data on HIV and monkeypox vaccine: updated statement (August 2022)"},"content":{"rendered":"<p><strong>Simon Collins, HIV i-Base<\/strong><\/p>\n<p><b><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-thumbnail wp-image-43297\" src=\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2022\/06\/typical-MPV-rash-on-hand-2-colour1-150x150.png\" alt=\"\" width=\"150\" height=\"150\" \/><\/strong>On 17 August 2022, BHIVA issued an updated statement on monkeypox (MPX) that includes information about vaccine efficacy, including in people living with HIV. [1]<\/b><\/p>\n<p>The statement summarises information about the time to develop antibody responses and how these continue to increase over four weeks after a single shot.<\/p>\n<p>One of the two HIV studies includes that responses might be slightly lower and take longer to develop in people who are HIV positive compared to HIV negative.<\/p>\n<p>Importantly, it recommends that people living with HIV should receive two shots of the vaccine, even though it might take several months before the second dose.<\/p>\n<p>When available, people who currently have a CD4 count &lt;200 cells\/mm<sup>3<\/sup> should be prioritised for the second dose.<\/p>\n<p>Having had a smallpox vaccination as a child will increase MPX antibodies after a single shot of the vaccine now. However, there is no evidence that the residual antibodies will prevent MPX infection now. fo example, 10% of 528 cases in the recent NEJM paper had received the smallpox vaccine as a child. [2]<\/p>\n<p><b>comment<\/b><\/p>\n<p><b>This update provides information that people can use when deciding their own levels of risk when returning to regular life.<\/b><\/p>\n<p><b>This is especially important given the limited access to vaccines and that further supplies in the UK are not expected for 1\u20132 months.<\/b><\/p>\n<p><b>Many people have already reduced their risk of exposure to MPX by changing how and when they have sex, given that this is only likely to be for a limited time, until vaccines become more widely available.<\/b><\/p>\n<p>References<\/p>\n<ol>\n<li>BHIVA rapid guidance on monkeypox virus. (Updated 17 August 2022).<br \/>\n<a href=\"https:\/\/www.bhiva.org\/BHIVA-rapid-guidance-on-monkeypox-virus\">https:\/\/www.bhiva.org\/BHIVA-rapid-guidance-on-monkeypox-virus<\/a><\/li>\n<li>International study of 528 monkeypox (MPX) cases: results from the 2022 outbreak need to inform new management guidelines. HTB (3 August 2022).<br \/>\n<a href=\"https:\/\/i-base.info\/htb\/43458\">https:\/\/i-base.info\/htb\/43458<\/a><\/li>\n<li>Collins S. Taking a break from monkeypox: four weeks out for August. HTB (3 August 2022).<br \/>\n<a href=\"https:\/\/i-base.info\/htb\/43686\">https:\/\/i-base.info\/htb\/43686<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base On 17 August 2022, BHIVA issued an updated statement on monkeypox (MPX) that includes information about vaccine efficacy, including in people living with HIV. [1] The statement summarises information about the time to develop antibody responses &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[323],"tags":[],"class_list":["post-43768","post","type-post","status-publish","format-standard","hentry","category-mpox"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/43768","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=43768"}],"version-history":[{"count":3,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/43768\/revisions"}],"predecessor-version":[{"id":43934,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/43768\/revisions\/43934"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=43768"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=43768"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=43768"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}