{"id":45548,"date":"2023-06-01T07:15:22","date_gmt":"2023-06-01T07:15:22","guid":{"rendered":"https:\/\/i-base.info\/htb\/?p=45548"},"modified":"2023-07-03T15:16:03","modified_gmt":"2023-07-03T15:16:03","slug":"tenofovir-reduces-risk-of-covid-19-in-pre-vaccine-studies","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/45548","title":{"rendered":"Tenofovir reduces risk of COVID-19 in pre-vaccine studies"},"content":{"rendered":"<div><\/div>\n<div>\n<p class=\"HTBsubhead3authorcredit\"><strong><span lang=\"EN-US\">Simon Collins, HIV i-Base<\/span><\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><strong><span lang=\"EN-US\">Long after most people will be following this research, several studies have reported a protective impact of tenofovir (TD or TAF) on the risk of catching SARS-CoV-2 and\/or on the severity of symptoms.<\/span><\/strong><\/p>\n<\/div>\n<div>\n<p class=\"HTBBODYtext\"><span lang=\"EN-US\">As a caution, including the latest study published in CID, this data is from the early COVID-19 epidemic, before vaccines became available. Results were seen both for people living with HIV taking ART and for HIV-negative people taking PrEP.<\/span><\/p>\n<p>The results remain controversial though as other adjusted observational studies continue to not find any protective associations. [3]<\/p>\n<\/div>\n<div>\n<p class=\"HTBreferences\"><span lang=\"EN-US\">References<\/span><\/p>\n<\/div>\n<div>\n<ol>\n<li class=\"HTBreferences\"><span lang=\"EN-US\">Lea AN et al. \u00a0HIV status, tenofovir exposure and the risk of poor COVID-19 outcomes: Real-world analysis from 6 United States cohorts before vaccine rollout. Clinical Infectious Diseases 76(10):1727\u20131734. (15 May 2023).<br \/>\n<\/span><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciad084\">https:\/\/doi.org\/10.1093\/cid\/ciad084<\/a><\/li>\n<li class=\"HTBreferences\">Julia del Amo. Question of whether tenofovir disoproxil fumarate\/emtricitabine provides protection against clinical severity of coronavirus disease. 2019\u00a0Clinical Infectious Diseases, 76(10):1735\u20131737. (15 May 2023).<span class=\"Apple-converted-space\">\u00a0<\/span><br \/>\n<a href=\"https:\/\/doi.org\/10.1093\/cid\/ciad086\">https:\/\/doi.org\/10.1093\/cid\/ciad086<\/a><\/li>\n<li class=\"HTBreferences\">Verburgh ML et al. No association between use of tenofovir disoproxil fumarate, etravirine, or integrase-strand transfer inhibitors and acquisition or severe outcomes of SARS-CoV-2 infection in people with HIV in the Netherlands. AIDS 37(9):p 1481-1486, July 15, 2023. | DOI: 10.1097\/QAD.0000000000003577<\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Simon Collins, HIV i-Base Long after most people will be following this research, several studies have reported a protective impact of tenofovir (TD or TAF) on the risk of catching SARS-CoV-2 and\/or on the severity of symptoms. As a caution, &hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282,278],"tags":[],"class_list":["post-45548","post","type-post","status-publish","format-standard","hentry","category-covid-19-hiv-and-covid-19-coinfection","category-covid-19"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/45548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=45548"}],"version-history":[{"count":5,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/45548\/revisions"}],"predecessor-version":[{"id":45742,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/45548\/revisions\/45742"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=45548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=45548"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=45548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}