{"id":4595,"date":"2001-06-30T13:57:45","date_gmt":"2001-06-30T12:57:45","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=4595"},"modified":"2014-06-12T13:33:27","modified_gmt":"2014-06-12T13:33:27","slug":"cd4-counts-predictive-of-musculoskeletal-manifestations-of-hiv-infection","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/4595","title":{"rendered":"CD4+ counts predictive of musculoskeletal manifestations of HIV infection"},"content":{"rendered":"<p><strong>Lymphocyte counts may be predictive of musculoskeletal problems in HIV-infected individuals, including infectious arthritis, which appears to be the most common musculoskeletal manifestation of HIV infection, according to a report by Spanish researchers.<\/strong><\/p>\n<p>Dr. Alejandro Olive and colleagues from Hospital Universitari Germans Trias i Pujol in Barcelona studied 74 HIV-infected patients with osteoarticular manifestations. Twenty-three percent of the patients had septic arthritis, with Staphylococcus aureus identified as the most common microorganism, according to the team&#8217;s report in the April issue of the Journal of Rheumatology.<\/p>\n<p>In addition, 12.2% of the patients had soft tissue infections, 8.1% had spondyloarthropathies, 12.2% had lymphomas, 8.1% had osteomyelitis and 32.4% had other miscellaneous conditions, which included arthralgia, gout, tendinitis and osteonecrosis.<\/p>\n<p>Among patients with septic arthritis, the mean CD4+ count was 164.7 cells\/mm3, for those with soft tissue infections it was 127.1 cells\/mm3, and for patients with spondyloarthropathies it was 245.8 cells\/mm3, Dr. Olive&#8217;s team found. Among patients with lymphoma, the mean CD4+ count was 132.8 cells\/mm3 and for those with osteomyelitis it was 233.6 cells\/mm3.<\/p>\n<p>Osteoarticular infections, the investigators found, always appeared when CD4+ counts were below 200 cells\/mm3, and pyomyositis and lymphoma appeared when CD4+ counts were below 150 cell\/mm3. &#8220;This suggests,&#8221; they say, &#8220;that musculoskeletal infections occur when HIV infection is advanced and that CD4+ counts may be predictive for particular musculoskeletal manifestations.&#8221;<\/p>\n<p>Reference:<\/p>\n<p>J Rheumatol 2001;28:802-804.<\/p>\n<p>Source: Reuters Health<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lymphocyte counts may be predictive of musculoskeletal problems in HIV-infected individuals, including infectious arthritis, which appears to be the most common musculoskeletal manifestation of HIV infection, according to a report by Spanish researchers. Dr. Alejandro Olive and colleagues from Hospital &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31],"tags":[],"class_list":["post-4595","post","type-post","status-publish","format-standard","hentry","category-opportunistic-infections-coinfections-and-complications"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/4595","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=4595"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/4595\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=4595"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=4595"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=4595"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}