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A short guide to articles in the October edition of HTB.<\/b><\/p>\nSimon Collins, HIV i-Base<\/b><\/p>\n
A short guide to articles in the October edition of HTB.<\/b><\/p>\n1. Editorial<\/h2>\n
https:\/\/i-base.info\/htb\/46445<\/a><\/p>\n This is an extra issue of HTB as we published enough articles last week to bring these forward from November.<\/strong><\/p>\n We lead with information about Uganda where human and civil rights abuses against LGBTQI+ people and people who support them have increased after the recent Anti-Homosexuality Act.<\/p>\n Other articles include IAS 2023 conference reports and other news – see below.<\/p>\n Uganda report: Increase in LGBTQI+ assaults and human rights violations need urgent activist responses Carefully documented cases of abuse from the first eight months of the year, together with recommendations on how this law needs to be overturned.<\/p>\n Our comment on the abuse also refers to speeches by the UK Home Secretary that support the atrocities in Uganda, including the death penalty, by not recognising these crimes as a reason to apply for asylum.<\/p>\n This is an issue that affects us all and that we can all help with.<\/p>\n https:\/\/i-base.info\/htb\/46424<\/a><\/p>\n Six more reports from this major conference held in Australia in July.<\/p>\n Reports on research include:<\/strong><\/p>\n First results from a small study using long acting cabotegravir\/rilpivirine injections<\/b> as first treatment, rather than a switch option. Many people who do not want to take daily pills might struggle if they have to become undetectable on oral pills first. Soon they might not have to. Summary of the 6-monthly lenacapavir injection<\/b> – including that the oral weekly pill also works. A review of studies on the immune-based treatments called bNAbs<\/b> which can be used for treatment and prevention. This cutting-edge research might let some people safely stop ART for a year and still keep viral load undetectable. And one of these studies – called RIO – is running in the UK. Dolutegravir<\/b> and adherence support can get viral load back to undetectable. Tiny study on using bitcegravir<\/b> during pregnancy – and our editorial comments show why even good news must be taken with caution. An essential first step if this new option is to become more widely available.<\/strong><\/p>\n The injections work but pricing complicates access compared to generic oral PrEP, that can be as low at $10 a month. Good news of course, this research does need to continue.<\/strong><\/p>\n But at least one high profile vaccine expert – Dr Anthony Fauci – who likely supported this work earlier – cautions on unlikely efficacy. Serious practical complications include how to run vaccine studies now that PrEP is widely available. The issue also includes several short reviews of recently published studies.<\/p>\n 6. A study reports that weight gain on ART<\/b> is a clinical concern for increasing the risk of other health problems – so needs to be taken seriously. 7. Drug resistance and the dapivirine vaginal ring<\/b> – an important consideration, but as with oral PrEP, many women only use the ring for a few months, rather than it becoming a long-term way to protect against HIV. Please see the full online articles about all these studies.<\/p>\n 8. Community survey on New-fill to correct facial fat loss<\/b><\/p>\n There is still time to give your views on this service in the UK.<\/strong><\/p>\n2. Special report<\/h2>\n
\n<\/b>https:\/\/i-base.info\/htb\/46384<\/a><\/p>\n3. IAS 2023: further reports<\/h2>\n
\nhttps:\/\/i-base.info\/htb\/46439<\/a><\/p>\n
\nhttps:\/\/i-base.info\/htb\/46406<\/a><\/p>\n
\nhttps:\/\/i-base.info\/htb\/46426<\/a><\/p>\n
\nhttps:\/\/i-base.info\/htb\/46331<\/a><\/p>\n
\nhttps:\/\/i-base.info\/htb\/46279 \u00a0<\/a><\/p>\n4. The EU approves injectable PrEP<\/h2>\n
\nhttps:\/\/i-base.info\/htb\/46320 <\/a><\/p>\n5. Early phase 1 study for potential HIV vaccine.<\/h2>\n
\nhttps:\/\/i-base.info\/htb\/46340<\/a><\/p>\nRecently published research<\/h2>\n
\nhttps:\/\/i-base.info\/htb\/46367<\/a><\/p>\n
\nhttps:\/\/i-base.info\/htb\/46362<\/a><\/p>\n