![\"\"](\"https:\/\/i-base.info\/htb\/wp-content\/uploads\/2025\/07\/IAS-2025-grphic-strip-IAS-620.png\")
<\/p>\n<\/p>\n
Simon Collins, HIV i-Base<\/strong><\/p>\n A poster presented at IAS 2025 included the complications and harm caused by the steady withdrawal of routine access to CD4 testing in many low- and middle-income countries. [2]<\/strong><\/p>\n This prospective study included 622 adults >15 years who were diagnosed with HIV at ten public health clinics in central Ethiopia between 2022-2024.<\/p>\n Median age was 35 and just under 60% were women.<\/p>\n Based on WHO staging alone, 229\/622 participants (37%) were categorised as Stage 1\/2. However, CD4 counts available for 118\/229 showed that one-third of those diagnosed as Stage 1\/2 actually had CD4 counts <200 cells\/mm3.<\/p>\n Using both staging and the available CD4 counts, 41% of the overall cohort were diagnosed as having advanced HIV. However, this will still be an underestimate because CD4 testing was only available for 35% overall.<\/p>\n AHD was more common among men (aOR 1.47 [95% CI: 1.01 to 2.16]), people >50 years (aOR 2.64 [95% CI: 1.18 to 5.90]) and rural residents (aOR 2.98 [95% CI: 1.56 to 5.67]).<\/p>\n The researchers concluded that lack of routine CD4 testing at initiation of ART led to missed identification of AHD in nearly one-third of people staged as WHO 1 or 2, who would then miss important investigations and interventions.<\/p>\n This shows that WHO staging is likely to underdiagnose rates of AHD when CD4 testing is not routinely available.<\/strong><\/p>\n Importantly, one of the changes to the new WHO guidelines presented at IAS 2025 is a new recommendation for CD4 count monitoring to be used for the management of AHD, rather than WHO staging. [2]<\/strong><\/p>\n Reference<\/p>\n Simon Collins, HIV i-Base A poster presented at IAS 2025 included the complications and harm caused by the steady withdrawal of routine access to CD4 testing in many low- and middle-income countries. [2] This prospective study included 622 adults >15 …<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,41,23,31],"tags":[344],"class_list":["post-52309","post","type-post","status-publish","format-standard","hentry","category-conference-reports","category-treatment-strategies","category-guidelines","category-opportunistic-infections-coinfections-and-complications","tag-ias-13th-kigali"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/52309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=52309"}],"version-history":[{"count":4,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/52309\/revisions"}],"predecessor-version":[{"id":52328,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/52309\/revisions\/52328"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=52309"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=52309"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=52309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}comment<\/h3>\n
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\nhttps:\/\/conference.ias2025.org\/media-758-advanced-hiv-disease-remains-common-among-people-with-hiv-newly-enrolled-to-care-in-centra<\/a><\/li>\n
\nhttps:\/\/i-base.info\/htb\/52185<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"