{"id":5291,"date":"2009-02-09T10:39:33","date_gmt":"2009-02-09T09:39:33","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=5291"},"modified":"2013-08-16T15:07:36","modified_gmt":"2013-08-16T15:07:36","slug":"drug-interactions-with-integrase-inhibitors","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/5291","title":{"rendered":"Drug interactions with integrase inhibitors"},"content":{"rendered":"<p><strong><a href=\"http:\/\/www.hiv-druginteractions.org\/\">http:\/\/www.hiv-druginteractions.org<\/a><\/strong><\/p>\n<p><strong>This is an outstanding review on the pharmacology of integrase inhibitors with a substantial section on raltegravir drug-drug interactions and elvitegravir drug-drug interactions.<\/strong><\/p>\n<p>There are four tables summarising all known interactions to date. The authors conclude that overall raltegravir has a low propensity for clinically meaningful drug interactions, whereas elvitegravir (with the presence of ritonavir) has modest potential for interactions.<\/p>\n<p>The review is highly recommended and will appear in 2009. An advance version is available online, but minor changes may still occur before final publication.<\/p>\n<p>Reference:<\/p>\n<p>Hazuda DJ et al. Emerging pharmacology: Inhibitors of Human Immunodeficiency Virus integration. Rev Pharmacol Toxicol, [Epub ahead of print]<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18928385\"><br \/>\nhttp:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18928385<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>http:\/\/www.hiv-druginteractions.org This is an outstanding review on the pharmacology of integrase inhibitors with a substantial section on raltegravir drug-drug interactions and elvitegravir drug-drug interactions. There are four tables summarising all known interactions to date. The authors conclude that overall raltegravir &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-5291","post","type-post","status-publish","format-standard","hentry","category-pk-and-drug-interactions"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/5291","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=5291"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/5291\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=5291"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=5291"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=5291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}