{"id":6627,"date":"2002-09-11T19:50:02","date_gmt":"2002-09-11T18:50:02","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=6627"},"modified":"2002-09-11T19:50:02","modified_gmt":"2002-09-11T18:50:02","slug":"the-switching-spiral-a-triumph-of-hope-over-benefit","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/6627","title":{"rendered":"The switching spiral: a triumph of hope over benefit?"},"content":{"rendered":"<p>from          The AIDS Reader<\/p>\n<p>Graeme          Moyle MD, MBBS<\/p>\n<p>The HIV therapy market          is expanding. Patients are not only living longer and therefore continuing          therapy but also taking more antiretroviral medications simultaneously.          Persons already receiving therapy represent the vast majority of the treatment          market; patients who are currently naive represent a minority at most          clinics. So, while there remains interest in competing over which drugs          to begin with, there is also considerable interest by pharmaceutical companies          in generating sales and gaining market share by encouraging physicians          to switch their patients from their current regimens, which have often          served them well for a number of years, to the new or alternative agents.          The usual justification, often based on short-term or even in vitro data,          is that the new or alternative drug carries a lower risk of causing or          contributing to a future adverse event.<\/p>\n<p><a href=\"http:\/\/www.medscape.com\/viewarticle\/434016?srcmp=aids-062102\">http:\/\/www.medscape.com\/viewarticle\/434016?srcmp=aids-062102<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>from The AIDS Reader Graeme Moyle MD, MBBS The HIV therapy market is expanding. Patients are not only living longer and therefore continuing therapy but also taking more antiretroviral medications simultaneously. Persons already receiving therapy represent the vast majority of &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[],"class_list":["post-6627","post","type-post","status-publish","format-standard","hentry","category-on-the-web"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/6627","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=6627"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/6627\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=6627"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=6627"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=6627"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}