{"id":7640,"date":"2005-01-29T15:10:48","date_gmt":"2005-01-29T14:10:48","guid":{"rendered":"http:\/\/moomango.co.uk\/htb\/?p=7640"},"modified":"2019-01-10T15:45:31","modified_gmt":"2019-01-10T15:45:31","slug":"us-treatment-guidelines-updated-2","status":"publish","type":"post","link":"https:\/\/i-base.info\/htb\/7640","title":{"rendered":"US treatment guidelines updated (Jan 2005)"},"content":{"rendered":"<p><strong>Updated guidelines on HIV treatment for adults and adolescents have been released by the U.S. Department of Health and Human Services (DHHS).<\/strong><\/p>\n<p><a href=\"https:\/\/aidsinfo.nih.gov\/guidelines\" rel=\"noopener\">https:\/\/aidsinfo.nih.gov\/guidelines<\/a><\/p>\n<p>Among the most important changes:<\/p>\n<ul>\n<li>Stavudine (d4T, Zerit) has been changed from a \u201cpreferred\u201d to an \u201calternative\u201d medication due to toxicity concerns, particularly facial wasting and neuropathy;<\/li>\n<li>The recently approved NRTI emtricitabine (FTC, Emtriva) has been added as an option to both the \u201cpreferred\u201d and \u201calternative\u201d lists of first-line regimens when used as part of a dual-NRTI backbone;<\/li>\n<li>The dual-NRTI backbone of tenofovir (Viread) plus lamivudine (3TC, Epivir) or emtricitabine is now recommended for protease inhibitor-based regimens as well as NNRTI-based regimens; and<\/li>\n<li>For asymptomatic, treatment-naive patients with CD4+ cell counts above 350, the viral load recommendation to defer or to consider therapy has been increased from 55,000 to 100,000 copies\/mL.<\/li>\n<\/ul>\n<p>The new guidelines also feature discussions on HIV treatment in specific subpopulations of patients, including adolescents, injection drug users and patients coinfected with hepatitis or tuberculosis.<\/p>\n<h2>Powerpoint Summaries of Updated DHHS Guidelines<\/h2>\n<p>Four sets of PowerPoint slide presentations, including author comments, are available from the\u00a0AIDS Education and Training Centers (AETC) National Resource Center.<\/p>\n<p><a href=\"http:\/\/www.aids-ed.org\">www.aids-ed.org<\/a><\/p>\n<p>Each slide presentation provides a review of the most important indications and recommendations together with speakers notes.<\/p>\n<ul>\n<li>Comprehensive Guideline Summary (44 slides)<\/li>\n<li>Initiation of Therapy (56 slides)<\/li>\n<li>Changing Therapy (30 slides)<\/li>\n<li>Special Issues (52 slides) includes acute HIV infection, treatment for adolescents, treatment for pregnant women, injection drug users, patients with HBV and HCV coinfection, TB, prevention counseling.<\/li>\n<\/ul>\n<p>Source: thebody.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Updated guidelines on HIV treatment for adults and adolescents have been released by the U.S. Department of Health and Human Services (DHHS). https:\/\/aidsinfo.nih.gov\/guidelines Among the most important changes: Stavudine (d4T, Zerit) has been changed from a \u201cpreferred\u201d to an \u201calternative\u201d &hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23],"tags":[],"class_list":["post-7640","post","type-post","status-publish","format-standard","hentry","category-guidelines"],"_links":{"self":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/7640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/comments?post=7640"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/posts\/7640\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/media?parent=7640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/categories?post=7640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/htb\/wp-json\/wp\/v2\/tags?post=7640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}