{"id":1012,"date":"2010-02-06T12:06:57","date_gmt":"2010-02-06T11:06:57","guid":{"rendered":"http:\/\/www.i-base.info\/qa\/?p=1012"},"modified":"2021-11-22T12:17:11","modified_gmt":"2021-11-22T12:17:11","slug":"sore-muscles-tiredness-and-feeling-irritable-on-treatment","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/1012","title":{"rendered":"Sore muscles, tiredness and feeling irritable on treatment"},"content":{"rendered":"<p>Thank you for your question.<\/p>\n<p>It is common for your body to need to adjust to treatment but things usually improve over the first few weeks.<\/p>\n<p>The tired muscles are difficult to explain but as with any symptom it is important to mention it to your doctor when you see him\/her next week.<\/p>\n<p>Exhaustion and irritability can be a related to taking efavirenz and is often related to sleep disturbance which can be a fairly common side-effect of efavirenz. These side-effects should start to lessen 2-4 weeks after starting medication. If they do not improve then again speak to your doctor about options to use <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hi,<\/p>\n<p>I have recently started treatment (last week). I am on efavirenz and Truvada and have adhered to it well missing no doses. I feel that my calf muscles and thighs are really sore shortly after I take my meds. I also feel absolutely exhausted and irritable.<\/p>\n<p>I am keen to persevere hoping that these are side effects that will disappear soon. I would be grateful of any advice you can give. My CD4 prior to starting was 330 and viral load 10, 000 or so.<\/p>\n<p>I have a meeting with my doc next week to review my progress.<\/p>\n<p>Thanks for all your help on here.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,38,39],"tags":[],"class_list":["post-1012","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-side-effects","category-starting-treatment"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/1012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=1012"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/1012\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=1012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=1012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=1012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}