{"id":11358,"date":"2016-05-12T01:28:01","date_gmt":"2016-05-12T01:28:01","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=11358"},"modified":"2016-05-12T01:31:33","modified_gmt":"2016-05-12T01:31:33","slug":"what-are-differences-in-side-effects-between-truimeq-and-stribild","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/11358","title":{"rendered":"Does Truimeq have fewer side effects that Stribild?"},"content":{"rendered":"<p>Hi<\/p>\n<p>It sounds like your doctor is giving you good information.<\/p>\n<p>Firstly, most people find adherence is easier with once-dailycompared to twice-daily combinations . So it is good that your doctor is suggesting this change.<\/p>\n<p>Secondly, <a href=\"https:\/\/i-base.info\/guides\/10303\">Triumeq<\/a>\u00a0probably does have a slightly reduced risk of side effects. This is because <a href=\"https:\/\/i-base.info\/guides\/8841\">Stribild<\/a>\u00a0includes a booster drug that in some people causes general side effects like nausea, tiredness and diarhhoea &#8211; even though these are usually mild.<\/p>\n<p>Another advantage is that Triumeq can be taken with or without food, but\u00a0Stribild needs to be taken with food.<\/p>\n<p>Anxiety has been reported with dolutegravir but generally in a very small percentage of people. In this case it would be easy to switch to Stribild as a second option.<\/p>\n<p>The other two drugs in Triumeq &#8211; abacavir and lamivudine (3TC) &#8211; are similar to the two drugs in Truvada &#8211; tenofovir DF and emtricitabine (FTC). Usually it is easy to switch between them but your doctor will use a blood test to check you are not at risk of a reaction to abacavir.<\/p>\n<p>This link on the i-Base website includes summary information on each HIV drug.<br \/>\n<a href=\"https:\/\/i-base.info\/guides\/category\/arvs\">https:\/\/i-base.info\/guides\/category\/arvs<\/a><\/p>\n<p>Each drug page also links to the full prescribing information for each drug on the European Medicines Agency (EMA) website.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>My doctor wants to change my treatment to a once a day regimen to avoid danger of me missing doses; as this happens occasionally with my twice daily regimen.<\/p>\n<p>To give you some background, I was diagnosed in September 2015 and instantly put on Truvada (one daily) and raltegravir (twice daily). I became undetectable and my CD4 returned to normal after about 6 weeks.\u00a0<\/p>\n<p>I&#8217;e just had my first 6 month follow up appointment and everything is still great, my viral load is 27 and all organs functioning normally. But my Dr wants me to change to once a day as the twice daily is sometimes not practical and i accidentally miss doses.<\/p>\n<p>My options are Triumeq or Stribild. I can&#8217;t seem to find much information on which one would be better with less side effects.<\/p>\n<p>I should point out that I suffer from anxiety and depression and my current medication exacerbates this slightly. Theres lots of warnings online about Triumeq causing anxiety and depression as one of its main side effect, but my doctor says its the best one with the least side effects?<\/p>\n<p>I basically need advice\u00a0about side effects of both Triumeq and Stribild and which one would be best. Or whether I should just keep to my current Truvada plus raltegravir regimen?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,10,38],"tags":[],"class_list":["post-11358","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-changing-treatment","category-side-effects"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/11358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=11358"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/11358\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=11358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=11358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=11358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}