{"id":12313,"date":"2016-10-17T00:46:53","date_gmt":"2016-10-17T00:46:53","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=12313"},"modified":"2016-10-17T00:48:06","modified_gmt":"2016-10-17T00:48:06","slug":"what-happens-if-my-current-combination-fails","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/12313","title":{"rendered":"What if my combination fails and can you help neuropathy?"},"content":{"rendered":"

Hi<\/p>\n

Thanks for your questions.<\/p>\n

First and easiest, is that if your viral load is currently undetectable and you don’t miss your meds, then this combination will not fail. You could use it for 20 years for example.<\/p>\n

Resistance can only develop in the following 3 ways:<\/p>\n

    \n
  1. If you are regularly late with meds or\u00a0miss doses.<\/li>\n
  2. If you don’t take atazanavir\/ritonavir with food – this is important, otherwise you only get half the dose.<\/li>\n
  3. If you take any other medicines that interact with your meds. Antacid tablets to settle your stomach can sometimes interact with atazanavir – so please talk to\u00a0your doctor\u00a0about this.<\/li>\n<\/ol>\n

    If you are careful about these three things, your current combination will not fail.<\/p>\n

    There will be other choice though in the future. For example a new drug called dolutegravir will soon be available as a generic medicine. This might help you feel more confident that there is a back up, just in case.<\/p>\n

    The neuropathy question is more difficult. This side effect of the early drugs you took – d4T and ddI – currently cannot be reversed. If this is causing pain, then some painkillers can sometimes work but please talk to your doctor about your choices.<\/p>\n

    More information about how to manage neuropathy is at this link.
    \nhttps:\/\/i-base.info\/guides\/side\/peripheral-neuropathy<\/a><\/p>\n\n","protected":false},"excerpt":{"rendered":"

    Hi,\u00a0I am HIV positive for 16 years and I am on\u00a0ART –\u00a0at present ATV\/R + Truvada on second line therapy. if fails are\u00a0many options are available in India? My life span is another 20 years to get it?\u00a0 neuropathy (ddi d4t) is chronic. how to deal this disease. please help.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,35,38,41],"tags":[],"class_list":["post-12313","post","type-post","status-publish","format-standard","hentry","category-adherence","category-all-topics","category-resistance","category-side-effects","category-support"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/12313","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=12313"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/12313\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=12313"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=12313"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=12313"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}